The use of dehydrogenase activity of micromycetes for quantification evaluation of antifunfal properties of biocides

Inglés. Filamentous fungi appear one of the most important agents causing biological deterioration of different materials utilized in the conditions of high temperature and humudity. The most effective method of materials&#039

Ruso. protection from fungal influence appears chemical treatment with fungicides. The main goal of the research presented in the article is represented by development of new methods of evaluation of fungicides&#039

efficiency. The scheme of a new method of analysis of antifungal propeties of preparations aimed on adjustment of dehydrogenese activity of filamentous fungi has been suggested. A new quantitative method for evaluation of the antifungal properties of the agents, which are based on the determination of dehydrogenase activity of filamentous fungi has been elaborated. Comparative quantitative parameter (DA) has been proposed to reduce measurement errors that have been obtained under intermediate precision. There has been established a high correlation degree of the test results of antifungal properties of drugs based upon PHMG obtained with the new and standard methods.

Разработан новый метод количественной оценки антифунгальных свойств препаратов, в основу которого положено определение дегидрогеназной активности мицелиальных грибов. Для уменьшения погрешности результатов испытаний, полученных в условиях промежуточной прецизионности, предложен относительный количественный параметр (DA). Установлена высокая степень корреляции полученных с помощью нового и стандартного методов результатов испытания антифунгальных свойств препаратов на основе полигексаме-тиленгуанидин гидрохлорида.