SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike
2021
Jenna J. Guthmiller | Olivia Stovicek | Jiaolong Wang | Siriruk Changrob | Lei Li | Peter Halfmann | Nai-Ying Zheng | Henry Utset | Christopher T. Stamper | Haley L. Dugan | William D. Miller | Min Huang | Ya-Nan Dai | Christopher A. Nelson | Paige D. Hall | Maud Jansen | Kumaran Shanmugarajah | Jessica S. Donington | Florian Krammer | Daved H. Fremont | Andrzej Joachimiak | Yoshihiro Kawaoka | Vera Tesic | Maria Lucia Madariaga | Patrick C. Wilson
With the ongoing pandemic, it is critical to understand how natural immunity against SARS-CoV-2 and COVID-19 develops. We have identified that subjects with more severe COVID-19 disease mount a more robust and neutralizing antibody response against SARS-CoV-2 spike protein.
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