Gold Nanoparticles and Nanorods in Nuclear Medicine: A Mini Review
2019
Daria Maccora | Valentina Dini | Chiara Battocchio | Ilaria Fratoddi | Antonella Cartoni | Dante Rotili | Massimo Castagnola | Riccardo Faccini | Isabella Bruno | Teresa Scotognella | Alessandro Giordano | Iole Venditti
In the last decade, many innovative nanodrugs have been developed, as well as many nanoradiocompounds that show amazing features in nuclear imaging and/or radiometabolic therapy. Their potential uses offer a wide range of possibilities. It can be possible to develop nondimensional systems of existing radiopharmaceuticals or build engineered systems that combine a nanoparticle with the radiopharmaceutical, a tracer, and a target molecule, and still develop selective nanodetection systems. This review focuses on recent advances regarding the use of gold nanoparticles and nanorods in nuclear medicine. The up-to-date advancements will be shown concerning preparations with special attention on the dimensions and functionalizations that are most used to attain an enhanced performance of gold engineered nanomaterials. Many ideas are offered regarding recent in vitro and in vivo studies. Finally, the recent clinical trials and applications are discussed.
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