Characterisation of a new molecule based on two E2 sequences from bovine viral diarrhoea-mucosal disease virus fused to the human immunoglobulin Fc fragment
2021
González Pose Alaín | Montesino Seguí Raquel | Maura Pérez Rafael | Hugues Salazar Florence | Cabezas Ávila Ignacio | Altamirano Gómez Claudia | Sánchez Ramos Oliberto | Roberto Toledo Jorge
Proper conformational arrangement of the E2 molecules of bovine viral diarrhoea-mucosal disease virus (BVD-MDV) is crucial to obtain an effective recombinant vaccine candidate against the disease. In this study, we characterised a new molecule composed of two distinct sequences of the E2 glycoprotein of BVD-MDV and the Fc fragment of human immunoglobulin (BVDE2Fc).
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