Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

2021

Tharaux, Pierre-Louis | Pialoux, Gilles | Pavot, Arthur | Mariette, Xavier | Hermine, Olivier | Resche-Rigon, Matthieu | Porcher, Raphaël | Ravaud, Philippe | Bureau, Serge | Dougados, Maxime | Tibi, Annick | Azoulay, Elie | Cadranel, Jacques | Emmerich, Joseph | Fartoukh, Muriel | Guidet, Bertrand | Humbert, Marc | Lacombe, Karine | Mahevas, Matthieu | Pene, Frédéric | Pourchet-Martinez, Valérie | Schlemmer, Frédéric | Yazdanpanah, Yazdan | Baron, Gabriel | Perrodeau, Elodie | Vanhoye, Damien | Kedzia, Cécile | Demerville, Lauren | Gysembergh-Houal, Anne | Bourgoin, Alexandre | Dalibey, Sarah | Raked, Nabil | Mameri, Lakhdar | Alary, Stéphanie | Hamiria, Samir | Bariz, Thinhinane | Semri, Hala | Hai, Dhiaa Meriem | Benafla, Moustafa | Belloul, Mohamed | Vauboin, Pernelle | Flamand, Saskia | Pacheco, Claire | Walter-Petrich, Anouk | Stan, Emilia | Benarab, Souad | Nyanou, Corine | Montlahuc, Claire | Biard, Lucie | Charreteur, Robin | Dupré, Celine | Cardet, Kévin | Lehmann, Blandine | Baghli, Kamyl | Madelaine, Claire | D'Ortenzio, Eric | Puéchal, Oriane | Semaille, Caroline | Savale, Laurent | Harrois, Anatole | Figueiredo, Samy | Duranteau, Jacques | Anguel, Nadia | Monnet, Xavier | Richard, Christian | Teboul, Jean-Louis | Durand, Philippe | Tissieres, Pierre | Jevnikar, Mitja | Montani, David | Bulifon, Sophie | Jaïs, Xavier | Sitbon, Olivier | Pavy, Stéphan | Noel, Nicolas | Lambotte, Olivier | Escaut, Lelia | Jauréguiberry, Stéphane | Baudry, Elodie | Verny, Christiane | Noaillon, Mathilde | Lefèvre, Edouard | Zaidan, Mohamad | Le Tiec, Clotilde Le Tiec | Verstuyft, Céline Verstuyft | Roques, Anne-Marie | Grimaldi, Lamiae | Molinari, Domitille | Leprun, Gaël | Fourreau, Alain | Cylly, Laurent | Virlouvet, Myriam | Meftali, Ramdane | Fabre, Solène | Licois, Marion | Mamoune, Asmaa | Boudali, Yacine | Georgin-Lavialle, Sophie | Senet, Patricia | Soria, Angèle | Parrot, Antoine | François, Hélène | Rozensztajn, Nathalie | Blin, Emmanuelle | Choinier, Pascaline | Camuset, Juliette | Rech, Jean-Simon | Canellas, Antony | Rolland-Debord, Camille | Lemarié, Nadège | Belaube, Nicolas | Nadal, Marine | Siguier, Martin | Petit-Hoang, Camille | Chas, Julie | Drouet, Elodie | Lemoine, Matthieu | Phibel, Audrey | Aunay, Lucie | Bertrand, Eliane | Ravato, Sylviane | Vayssettes, Marie | Adda, Anne | Wilpotte, Celine | Thibaut, Pélagie | Fillon, Julie | Debrix, Isabelle | Fellahi, Soraya | Bastard, Jean-Philippe | Lefèvre, Guillaume | Fallet, Vincent | Gottenberg, Jacques-Eric | Hansmann, Yves | Andres, Emmanuel | Bayer, Sophie | Becker, Guillaume | Blanc, Frédéric | Brin, Stéphane | Castelain, Vincent | Chatelus, Emmanuel | Chatron, Eva | Collange, Olivier | Danion, François | De Blay, Frédéric | Demonsant, Eric | Diemunsch, Pierre | Diemunsch, Sophie | Felten, Renaud | Goichot, Bernard | Greigert, Valentin | Guffroy, Aurélien | Heger, Bob | Hutt, Anne | Kaeuffer, Charlotte | Kassegne, Loic | Korganow, Anne Sophie | Le Borgne, Pierrick | Lefebvre, Nicolas | Martin, Tristan | Mertes, Paul Michel | Metzger, Catherine | Meyer, Nicolas | Nisand, Gabriel | Noll, Eric | Oberlin, Mathieu | Ohlmann-Caillard, Sophie | Poindron, Vincent | Pottecher, Julien | Ruch, Yvon | Sublon, Cédric | Tayebi, Hakim | weill, françois | Mekinian, Arsène | Chopin, Dorothée | Fain, Olivier | Garnier, Marc | Krause le Garrec, Jessica | Morgand, Marjolaine | Pacanowski, Jerome | Urbina, Tomas | McAvoy, Chloe | Pereira, Maria | Aratus, Gladys | Berard, Laurence | Simon, Tabassome | Daguenel-Nguyen, Anne | Antignac, Marie | Leplay, Céline | Arlet, Jean-Benoit | Diehl, Jean-Luc | Bellenfant, Florence | Blanchard, Anne | Buffet, Alexandre | Cholley, Bernard | Fayol, Antoine | Flamarion, Edouard | Godier, Anne | Gorget, Thomas | Hamada, Sophie-Rym | Hauw-Berlemont, Caroline | Hulot, Jean-Sébastien | Lebeaux, David | Livrozet, Marine | Michon, Adrien | Neuschwander, Arthur | Penet, Marie-Aude | Planquette, Benjamin | Ranque, Brigitte | Sanchez, Olivier | Volle, Geoffroy | Briois, Sandrine | Cornic, Mathias | Elisee, Virginie | Jesuthasan, Denis, | Djadi-Prat, Juliette | Jouany, Pauline | Junquera, Ramon | Henriques, Mickael | Kebir, Amina | Lehir, Isabelle | Meunier, Jeanne | Patin, Florence | Paquet, Valérie | Tréhan, Anne | Vigna, Véronique | Sabatier, Brigitte | Bergerot, Damien | Jouve, Charléne | Knosp, Camille | Lenoir, Olivia | Mahtal, Nassim | Resmini, Léa | Lescure, F-Xavier | Ghosn, Jade | BACHELARD, Antoine | BIRONNE, Timothee | Borie, Raphael | BOUNHIOL, Agathe | Boussard, Catherine | CHAUFFiER, Jeanne | CHALAL, Solaya | CHALAL, Lynda | CHANSOMBAT, Malikhone | CRESPIN, Paul | Crestani, Bruno | DACONCEICAO, Olivia | DECONINCK, Laurene | Dieude, Philippe | Dossier, Antoine | Dubert, Marie | DUCROCQ, Greggory | Fuentes, Axelle | Gervais, Anne | GILBERT, Marie | ISERNIA, Valentina | Ismael, Sophie | Joly, Veronique | JULIA, Zelie | Lariven, Sylvie | Le Gac, Sylvie | LE PLUART, Diane | LOUNI, Francoise | Ndiaye, Awa | Papo, Thomas | PARISEY, Marion | Phung, Bao | Pourbaix, Annabelle | Rachline, Anne | Rioux, Christophe | SAUTEREAU, Aurelie | Steg, Gabriel | TARHINI, Hassan | VALAYER, Simon | VALLOIS, Dorothee | VERMES, Paul | VOLPE, Thomas | Nguyen, Yann | Honsel, Vasco | Weiss, Emmanuel | Codorniu, Anaïs | Zarrouk, Virginie | de Lastours, Victoire | Uzzan, Matthieu | Olivier, Olivier | Rossi, Geoffrey | Gamany, Naura | Rahli, Roza | Louis, Zeina | Boutboul, David | Galicier, Lionel | Amara, Yaël | Archer, Gabrielle | Benattia, Amira | Bergeron, Anne | Bondeelle, Louise | De Castro, Nathalie | Clément, Melissa | Darmont, Michaël | Denis, Blandine | Dupin, Clairelyne | Feredj, Elsa | Feyeux, Delphine | Joseph, Adrien | Lengliné, Etienne | Le Guen, Pierre | Liégeon, Geoffroy | Lorillon, Gwenaël | Mabrouki, Asmaa | Mariotte, Eric | Martin de Frémont, Grégoire | Mirouse, Adrien | Molina, Jean-Michel | Peffault De Latour, Régis | Oksenhendler, Eric | Saussereau, Julien | Tazi, Abdellatif | Tudesq, Jean-Jacques | Zafrani, Lara | Brindele, Isabelle | Bugnet, Emmanuelle | Celli Lebras, Karine | Chabert, Julien | Djaghout, Lalia | Fauvaux, Catherine | Jegu, Anne Lise | Kozaliewicz, Ewa | Meunier, Martine | Tremorin, Marie-Thérèse | Davoine, Claire | Madeleine, Isabelle | Caillat-Zucman, Sophie | Delaugerre, Constance | Morin, Florence | Sene, Damien | BURLACU, Ruxandra | Chousterman, Benjamin | Megarbane, Bruno | Richette, Pascal | Riveline, Jean-Pierre | Frazier, Aline | Vicaut, Eric | BERTON, Laure | HADJAM, Tassadit | VASQUEZ-IBARRA, Miguel Alejandro | Jourdaine, Clément | Jacob, Aude | SMATI, Julie | Renaud, Stéphane | Manivet, Philippe | PERNIN, Claire | SUAREZ, Lydia | Semerano, Luca | ABAD, Sebastien | Benainous, Ruben | Bloch Queyrat, Coralie | Bonnet, Nicolas | Brahmi, Sabrina | Cailhol, Johann | Cohen, Yves | Comparon, Celine | Cordel, Hugues | Dhote, Robin | Dournon, Nathalie | Duchemann, Boris | Ebstein, Nathan | Giroux-Leprieur, Benedicte | Goupil de Bouille, Jeanne | Jacolot, Anne | Nunes, Hilario | Oziel, Johanna | Rathouin, Vanessa | Rigal, Marthe | Roulot, Dominique | Tantet, Claire | Uzunhan, Yurdagul | Costedoat-Chalumeau, Nathalie | Ait Hamou, Zakaria | Benghanem, Sarah | BLANCHE, Philippe | Canoui, Etienne | Carlier, Nicolas | Chaigne, Benjamin | Contejean, Adrien | Dunogue, Bertrand | DUPLAND, Pierre | DUREL - MAURISSE, Aurélie | Gauzit, Remy | Jaubert, Paul | Joumaa, Hassan | Jozwiak, Mathieu | Kerneis, Solen | LACHATRE, Marie | Lafoeste, Hélène | Legendre, Paul | Luong Nguyen, Liem Binh | Marey, Jonathan | MORBIEU, Caroline | Mouthon, Luc | Nguyen, Lee | Palmieri, Lola-Jade | Regent, Alexis | Szwebel, Tali-Anne | Terrier, Benjamin | GUERIN, Corinne | ZERBIT, Jérémie | CHEREF, Kahina | CHITOUR, Kamil | CISSE, Mamadou Salif | CLARKE, Ada | Clavere, Gaelle | DUSANTER, Isabelle | GAUDEFROY, Caroline | Jallouli, Moez | Kolta, Sami | LE BOURLOUT, Catherine | Marin, Nathalie | MENAGE, Nathalie | MOORES, Alexandre | PEIGNEY, Isabelle | PIERRON, Cédric | SALEH-MGHIR, Samira | VALLET, Mathilde | Michel, Marc | Melica, Giovanna | Lelievre, Jean-Daniel | Fois, Elena | Lim, Pascal | Matignon, Marie | Guillaud, Constance | THIEMELE, Alaki | Schmitz, David | BOUHRIS, Marion | BELAZOUZ, Syllia | Languille, Laetitia | MEKONTSO-DESSAPS, Armand | SADAOUI, Thiziri | Mayaux, Julien | Cacoub, Patrice | Corvol, Jean-Christophe | Louapre, Céline | Sambin, Sara | Mariani, Louise-Laure | Karachi, Carine | Tubach, Florence | Estellat, Candice | Gimeno, Linda | Martin, Karine | Bah, Aïcha | Keo, Vixra | Ouamri, Sabrine | Messaoudi, Yasmine | Yelles, Nessima | Faye, Pierre | Cavelot, Sébastien | Larcheveque, Cecile | Annonay, Laurence | Benhida, Jaouad | Zahrate-Ghoul, Aida | Hammal, Soumeya | Belilita, Ridha | Lecronier, Marie | Beurton, Alexandra | Haudebourg, Luc | Deleris, Robin | Le Marec, Julien | Virolle, Sara | Nemlaghi, Safaa | Bureau, Côme | Mora, Pierre | De Sarcus, Martin | Clovet, Olivier | Duceau, Baptiste | Grisot, Paul Henri | Pari, Marie Hélène | Arzoine, Jérémy | Clarac, Ulrich | Faure, Morgane | Delemazure, Julie | Decavele, Maxence | Morawiec, Elise | Demoule, Alexandre | Dres, Martin | Vautier, Mathieu | Allenbach, Yves | Benveniste, Olivier | Leroux, Gaelle | Rigolet, Aude | GUILLAUME-JUGNOT, PERRINE | Domont, Fanny | Desbois, Anne claire | Comarmond, Cloé | Champtiaux, Nicolas | Toquet, Segolene | Ghembaza, Amine | Vieira, Matheus | Maalouf, Georgina | Boleto, Gonçalo | Ferfar, Yasmina | Charbonnier, Fanny | Aguilar, Claire | Alby-Laurent, Fanny | Alyanakian, Marie-Alexandra | BAKOUBOULA, Prissile | Broissand, Christine | BURGER, Carole | CAMPOS-VEGA, Clara | Chavarot, Nathalie | Choupeaux, Laure | Fournier, Benjamin | GRANVILLE, Sophie | ISSORAT, Elodie | Rouzaud, Claire | VIMPERE, Damien | Geri, Guillaume | Derridj, Nawal | Sguiouar, Naima | Meddah, Hakim | Djadel, Mourad | Chambrin-Lauvray, Helene | Duclos-Vallée, Jean-Charles | Saliba, Faouzi | Sacleux, Sophie-Caroline | Koumis, Ilias | Michot, Jean-Marie | Stoclin, Annabelle | Colomba, Emeline | Pommeret, Fanny | Willekens, Chistophe | Sakkal, Madona | Da Silva, Rosa | Dejean, Valérie | Mekid, Yasmina | Ben-Mabrouk, Ines | Pradon, Caroline | Drouard, Laurence | Camara-Clayette, Valérie | Morel, Alexandre | Garcia, Gilles | Mohebbi, Abolfazl | Berbour, Férial | Dehais, Mélanie | Pouliquen, Anne-Lise | Klasen, Alison | Soyez-Herkert, Loren | London, Jonathan | Keroumi, Younes | Guillot, Emmanuelle | Grailles, Guillaume | El Amine, Younes | Defrancq, Fanny | Fodil, Hanane | Bouras, Chaouki | Dautel, Dominique | Gambier, Nicolas | Dieye, Thierno | Razurel, Anaïs | Bienvenu, Boris | Lancon, Victor | Lecomte, Laurence | Beziriganyan, Kristina | Asselate, Belkacem | Allanic, Laure | Kiouris, Elena | Legros, Marie-Hélène | Lemagner, Christine | Martel, Pascal | Provitolo, Vincent | Ackermann, Félix | LE MARCHAND, Mathilde | Clan Hew Wai, Aurélie | Fremont, Dimitri | Coupez, Elisabeth | Adda, Mireille | Duée, Frédéric | Bernard, Lise | Gros, Antoine | Henry, Estelle | Courtin, Claire | Pattyn, Anne | Guinot, Pierre-Grégoire | Bardou, Marc | Maurer, Agnes | Jambon, Julie | Cransac, Amélie | Pernot, Corinne | Mourvillier, Bruno | Servettaz, Amélie | Deslée, Gaetan | Wynckel, Alain | Benoit, Philippe | Marquis, Eric | Roux, Damien | Gernez, Coralie | Yelnik, Cécile | Poissy, Julien | Nizard, Mandy | Denies, Fanette | Gros, Hélène | Mourad, Jean-Jacques | Sacco, Emmanuelle | Renet, Sophie