Experimental copper and Heliotropium europaeum [heliotrope] intoxication in sheep: clinical syndromes and trace element concentrations
1991
Howell, J.McC. | Doel, H.S. | Dorling, P.R. (Murdoch Univ., Murdoch (Australia). School of Veterinary Studies)
A total of 14 Merino wethers were given Cu and heliotrope concurrently (9 sheep) or heliotrope alone for 12 weeks then Cu starting 8 weeks after heliotrope consumption ceased (5 sheep). Clinically and biochemically there were no significant differences between the 2 regimes. Of 13 sheep which showed clinical signs, 3 developed haemolysis, 8 became jaundiced and 2 became weak without jaundice. The concentration of Cu in the liver of animals fed Cu alone increased to twice, and in groups fed Cu and heliotrope it increased to 3 times the control level.
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