Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge) [sheep]

Huxtable, C.R.; Dorling, P.R.; Colegate, S.M. . School of Veterinary Studies

Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge) [sheep]

1993

Huxtable, C.R. | Dorling, P.R. | Colegate, S.M. (Murdoch Univ. (Australia). School of Veterinary Studies)

An isoprenyl guanidine, galegine, was isolated from the Western Australian sedge Schoenus asperocarpus (Cyperaceae). Synthetic galegine was shown to reproduce the clinical and pathological features of poisoning of this plant. Preliminary results suggest that the massive thoracic effusion observed in sedge poisoning is the result of a direct effect on pulmonary vascular permeability.

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