Ameliorative effect of synthetic γ-aminobutyric acid (GABA) on performance traits, antioxidant status and immune response in broiler exposed to cyclic heat stress

Ameliorative effect of synthetic γ-aminobutyric acid (GABA) on performance traits, antioxidant status and immune response in broiler exposed to cyclic heat stress

2016

The aim of this study was to find the effect of synthetic γ-aminobutyric acid (GABA) on the performance, antioxidant status, and immune response in broiler exposed to summer stress. A total of 400-day-old male broiler chickens (Ross 308) was randomly distributed into five treatments (5 replicates). One group served as a control (basal diet only) while the others were supplemented with GABA at the rate of 25 (GABA-25), 50 (GABA 50), 75 (GABA-75), and 100 (GABA-100) mg/kg feed. The experiment was continued for 35 days. Feed intake during the third week was significantly higher (P < 0.05) in GABA-75 and GABA-100, however, it increased significantly (P < 0.05) in GABA-100 during the fourth and fifth week. Overall mean feed intake was significantly (P < 0.05) high in GABA-75 and GABA-100. From the results, we found that body weight improved significantly (P < 0.05) in GABA-50 in week-3. During the fourth, fifth, and overall, body weight increased significantly (P < 0.05) in GABA-100. Significantly, high (P < 0.05) feed conversion ratio (FCR) was found in GABA-100 during the third, fourth, fifth, and on an overall basis. Mean Malondialdehyde (MDA) decreased significantly (P < 0.05) in GABA-100 while Paraoxonase (PON1) and Newcastle disease (ND) titer increased significantly (P < 0.05) in the same group. We concluded that performance traits, antioxidant status, and immune response improved in broiler supplemented 100 mg/kg GABA, exposed to cyclic heat stress.

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