Access to Phosphine-Containing Quinazolinones Enabled by Photo-Induced Radical Phosphorylation/Cyclization of Unactivated Alkenes
2022
Mu, Binsong | Zhang, Le | Lv, Guanghui | Chen, Kang | Wang, Ting | Chen, Jian | Huang, Tianle | Guo, Li | Yang, Zhongzhen | Wu, Yong
A mild and facile photo-induced cascade radical addition/cyclization of unactivated alkenes has been reported, through which a variety of biologically valuable phosphine-containing quinazolinones could be obtained in moderate to good yields. The protocol was characterized by mild conditions, broad substrate scope, and high atomic economy.
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