Epidermal growth factor-like activity in mares' milk

Murray, M.J.; Schaudies, R.P.; Cavey, D.M.

Epidermal growth factor-like activity in mares' milk

1992

Murray, M.J. | Schaudies, R.P. | Cavey, D.M.

Epidermal growth factor (EGF)-like activity was measured in mares' colostrum and milk by radioreceptor assay. Milk samples were collected from 22 mares 1 or more times during early lactation. Samples of colostrum were taken after parturition and before the foal first suckled (presuckle), within 6 hours after the foal first suckled (postsuckle), and on days 1, 2, 4, and 8 of lactation. In the 5 mares from which milk samples were obtained at each sampling time, presuckle colostral mean EGF-like activity (17.8 ng/ml) was greatest (P < 0.05). The mean values for EGF-like activity at all other sampling times were not significantly different from each other (postsuckle colostrum, 9.7 ng/ml; day 1, 9.6 ng/ml; day 2, 8.5 ng/ ml; day 4, 8.0 ng/ml; day 8, 7.8 ng/ml).

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