Cascade Amination and Acetone Monoarylation with Aryl Iodides by Palladium/Norbornene Cooperative Catalysis
2017
Fu, Wai Chung | Zheng, Bin | Zhao, Qingyang | Chan, Wesley Ting Kwok | Kwong, Fuk Yee
A palladium/norbornene cocatalyzed three-component reaction of aryl iodides, O-benzoylhydroxylamines, and acetone is reported. o′-Aminoaryl acetones or o,o′-diaminoaryl acetones are efficiently prepared via tandem ortho-C–H amination/ipso-C–I α-arylation sequence, and the regiospecificity has been confirmed by X-ray analysis. The proposed method addresses the condensation/amination of free-N-H-bearing substrates in acetone monoarylations and the synthesis of extremely congested 2,6-disubstituted aryl acetones.
Mostrar más [+] Menos [-]Palabras clave de AGROVOC
Información bibliográfica
Este registro bibliográfico ha sido proporcionado por National Agricultural Library
