Acid ionic liquid promoted addition of C(sp3)–H bond to aldehyde
2014
Zhang, Xue-Yan | Dong, Dao-Qing | Yue, Tao | Hao, Shuang-Hong | Wang, Zu-Li
A novel protocol for acid ionic liquid promoted C(sp³)–H bond functionalization of alkyl azaarenes and nucleophilic addition to aldehydes was developed in good to excellent yields, which provides an efficient approach for the synthesis of alkyl-substituted azaarene derivatives. It is worthwhile to note that acid ionic liquid used for this reaction can be recycled and reused six times without a significant decrease in activity.
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