Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
2010
Jürgen Kurt Rockstroh | Jan van Lunzen | Stefan Schmiedel | Hüseyin Sirma | Christian Noah | Knud Schewe | Oliver Schildgen
A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years.
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