Epigenetics Regulators of Genomic Imprinting in Mammals
2016
Zeynep Demirtaş | Fatih Bilgi | Levent Mercan
Genomic imprinting is expression of gene’s only one allele in one of homolog chromosome depending on its maternal or paternal origin. A waste number of genes which are under the imprinting effect were identified as it has a key role in mammalian growth. The first three genes which is identified as imprinted are Igf2r, Igf2 and H19 which are first discovered in mouse genome. Over a hundred genes are identified as imprinted in mammals. Most of the imprinted genes are considered as they have a key role in growth and differentiation. In this review, epigenetic regulators of imprinted genes in mammals were mentioned.
Mostrar más [+] Menos [-]Información bibliográfica
Este registro bibliográfico ha sido proporcionado por Directory of Open Access Journals
