APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
2021
Ping An | Efe Sezgin | Gregory D. Kirk | Priya Duggal | Elizabeth Binns-Roemer | George Nelson | Sophie Limou | Mark L. Van Natta | Douglas A. Jabs | Michelle Estrella | Jeffrey B. Kopp | Cheryl A. Winkler
An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.
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