ANTIBACTERIAL ACTIVITY OF THE SOLASODINE OF SOLANUM NIGRUM AGAINST BACTERIAL ISOLATES FROM THE WOUNDS
2009
Hammed Gadoh Abbas | Mohammed Abdul-Imam Almazini | Amani Abdul-Amer
In this study , 80 clinical samples collected from patients including wound, blood, urine and cerebrospinal fluid and isolates of Gram-positive and Gram-negative bacteria were identified . The inhibitory effects of ethyl alcohol extracts and solasodine compound of Solanum nigrum were tested on clinical isolates of the wound included: Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa. The ethyl alcohol extract showed inhibitory activity on all tested bacterial Spp . All the activities were compared with a tetracycline.The Minimum Inhibitory Concentration (MIC) of the Solasodine were 8, 6, 4, 8 mg/ml respectively for S. aureus , S. epidermidis , E. coli and P. aeruginosa respectively .The results lend scientific credence to justify the use of the Solasodine compound against bacterial isolates of the wounds and some bacterial diseases
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