STUDY OF AMERICAN  COCKROACH ALLERGY DISTRIBUTION AND ITS ASSOCIATION WITH  SOME HLA- DQ AND - DR ALLELES IN ATOPIC PATIENTS IN BASRAH PROVINCE / IRAQ

Huda K. Kareem; Fawziah A. Abdullah; Dhia K. Kareem

STUDY OF AMERICAN COCKROACH ALLERGY DISTRIBUTION AND ITS ASSOCIATION WITH SOME HLA- DQ AND - DR ALLELES IN ATOPIC PATIENTS IN BASRAH PROVINCE / IRAQ

2016

Huda K. Kareem | Fawziah A. Abdullah | Dhia K. Kareem

Ninety six for each healthy(n=96)and atopic,(n=96)individuals duals from the same geographical region, paired by sex and age, their sera specific IgE antibodies were estimated by enzyme linked immune sorbent assay test (ELISA) and genotyped by polymerase chain reaction based onHLA-DQB1*0602, HLA-DQB1*0604 andHLA-DRB1*12. The specific IgE based on ELISA results revealed that Out of 96 only59 (61.5%) of atopic patients were sensitive to CR allergen. The association between sensitivity to CR allergen and age was considered to be not statistically significant (P>0.05).However the higher rate of CR allergens sensitivity(62.9%) was observed in first age group(

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