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The biocatalytic conversion of 8-hydroxymanzamine A to manzamine A Texto completo
2003
Kasanah, N. | Rao, K.V. | Yousaf, M. | Wedge, D.E. | Hamann, M.T.
The selective dehydroxylation of 8-hydroxymanzamine A (...1) to form manzamine A (...2) can be completed by fermentation with Fusarium solani or Streptomyces seokies. This unique biocatalytic conversion is important due to the fact that manzamine A has more desirable biological activity when assayed in a murine model against malaria.
Mostrar más [+] Menos [-]Synthesis of oligoenynes and oligomeric conjugated diacetylenes
2003
Polhuis, M. | Hendrikx, C.C.J. | Zuilhof, H. | Sudhölter, E.J.R.
Malettinin A: a new antifungal tropolone from an unidentified fungal colonist of Hypoxylon stromata (NRRL 29110) Texto completo
2003
Angawi, Rihab F. | Swenson, Dale C. | Gloer, James B. | Wicklow, Donald T.
Malettinin A (1) has been isolated from cultures of an unidentified fungus encountered as a colonist of Hypoxylon stromata. The structure of 1 was proposed by analysis of NMR and MS data, and confirmed by X-ray diffraction analysis of a methanol adduct. Malettinin A shows significant activity in assays against Aspergillus flavus. Malettinin A (1) has been isolated from cultures of an unidentified fungus encountered as a colonist of Hypoxylon stromata. The structure of 1 was proposed by analysis of NMR and MS data, and confirmed by X-ray diffraction analysis of a methanol adduct. Malettinin A shows significant activity in assays against Aspergillus flavus.
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