Three cancer cell lines, i.e. HEpG-2 (human liver carcinoma), MCF-7 (human breast adeno-carcinoma), and PC3 (Prostatic Small Cell Carcinoma) were used to determine the cytotoxic effects of the neonicotinoid insecticide (imidacloprid) and conazole fungicide (myclobutanil). Cytotoxicity was measured by neutral red incorporation (NRI) assay. The lowest concentration of the tested pesticides (0.5 μg/ml) was toxic. With the increase of the concentration up to 80 μg/ml, the Department of plant protection, Faculty of Agric., Ain Shams University, shoubra  Elkheima, Cairo, Egypt Department of Genetics, Faculty of Agric., Ain Shams University, Cairo, Egypt damage degree of the cellular form and size was more serious. The midpoint cytotoxicity value, (NRI50) for imidacloprid and myclobutanil for HEpG-2, MCF-7, and PC3 cancer cell lines were 110.5, 67.7 and 67.6 μg/ml and 38.12, 41 and 27.5 μg/ml, respectively. In general, myclobutanil was very toxic in the three cancer cell lines compared with imidacloprid.

Egypt suffers from future risks due to lack of water especially in the downstream countries, Egypt and Sudan, which depend on the Nile water almost entirely and the upstream countries are moving to raise problems with Egypt and erect dams and pressure on Egypt to achieve the greatest economic benefit possible to prevent Egypt from horizontal agricultural expansion. Egypt is the largest and most dependent country on Nile water, with almost no rainfall. Groundwater is not renewable. Thus, the Nile water accounts for about 97% of Egypt's water resources and the share of the Egyptians is 55.5 billion m3, this quantity of water is insufficient to the needs of the population, and in order to maintain Egypt's per capita water, it needs about 80 billion m3, which means a deficit of 25 billion m3 and stability of Egypt's share of the Nile water under current local, regional and global conditions, and development of the appropriate strategy to alleviate the conflict with the basin countries Nile River so the study aimed to compare production efficiency and the economics of the irrigation systems used in the province of the lake through the study of water user associations in agriculture under the different irrigation patterns within water users association and outside association to rationalize the use of water and raising awareness to increase productivity. The results of the estimation indicated that the economic efficiency indicators of the maize and potato crop farmers in the sample of the field study show the preference of the use of the production function in the logarithmic formula to the different variables affecting the productivity of the crops according to the irrigation systems within the water user associations The results showed that the total production elasticity of maize crop was about 0.720, 0.530, 0.348 for sprinkler & drop, developed irrigation, and padded flooding systems, while the value of (R2) was about 0.76 , 0.60, 0.63  for irrigation systems respectively, The results showed that the total productivity of the potato crop was 1.127, 1.16, 1.318, for sprinkler & drop, developed irrigation, and padded flooding systems respectively, while the value of (R2) was about 0.76, 0.62, 0.70 for irrigation systems respectively. The relationship between the total costs and quantity produced of maize, which showed that the quadratic formula is the best formulas for the data, and the equations show that there is a statistically significant positive relationship between the total costs and production of maize in Behera Governorate. In the estimation of the optimal production volume, which reduces the costs is estimated at about 18.7, 22.1, 23.9 ardab/feddan, for sprinkler & drop, developed irrigation, and padded flooding systems respectively. In the estimation of the production volume which maximizes profit, the results showed that this volume was not reached, 29.1, 36.1, 31.9 ardab/feddan, for sprinkler & drop, developed irrigation, and padded flooding systems respectively. Calculating cost elasticity, it reached about 1.19, 0.804, 0.719, for sprinkler & drop, developed irrigation, and padded flooding systems respectively. In order to determine the optimal production volume of the potato crop, which reduces the costs, so make average cost equal marginal costs, estimated  at 12.539, 11.377, 11.064 tons/fed, for sprinkler & drop, developed irrigation, and padded flooding systems respectively. The size of production of potato that maximizes profit was about 42,500, 33.350, 25.600 tons/fed, for sprinkler & drop, developed irrigation, and padded flooding systems respectively. Calculating the cost elasticity of the potato, it turned out that it was about 0.93, 0.804, 0.719 for sprinkler & drop, developed irrigation, and padded flooding systems respectively. Production efficiency measures are (7), the study of the efficiency of production of maize crop for members of water associations in the sample of the study in Behera Governorate. It was found that the members of the water users association of developed irrigation for in the feddan productivity of maize was exceeded, which was estimated at 23.01 ardab/feddan, while it reached about 19.05, 22.1 ardab/feddan for sprinkler & drop, and flooding systems respectively. Increase the total revenues of the members of water user associations to developed irrigation system for the maize crop, estimated at 8744.7 pounds/feddan while it reached about 7239, 8402.2 pounds/fed for members of the water associations that use sprinkler & drop, and flooding systems respectively.   Increase in return of maize crop for members of water associations users of developed irrigation system, which amounted to about 3529.3 pounds while estimated at about 2204.8, 3270.1 pounds for members of water use associations for sprinkler & drop, and flooding systems respectively. Increase in the profitability of the pound for water use associations of developed irrigation system, which amounted to about 0.677 pounds, the ratio of the total return on the costs of the members of water use associations to flooding irrigation and developed irrigation, estimated at 2.03, 2.07 while estimated at 1.71 sprinkler irrigation, members of water user associations of the developed irrigation system was  exceeded, where the return of cubic meter of water reached about 3.53 pounds, and the productivity of the cubic meter of water for the members of the water user associations showed that the irrigation system of sprinkling and drip was about 5.6 for maize crop. The members of water use associations of for sprinkler & drop irrigation in the potato productivity was exceeded, estimated at 11.250 tons/fed, increase the total income of The members of water use associations of irrigation sprinkling and drip of potato crop, estimated at about 33750 pounds/ fed, shows the increase yield of potato crop members of links irrigation sprinkler system, where reached about 11300 pound. Increase in the profitability of the pound for the members of sprinkler irrigation system, it was about LE 0.5. The members of the water users association of the sprinkler and drip irrigation system, was exceeded, where the return of the use of cubic meters of water was about 18.9 pounds. Showing the return of the use of cubic meters of water for the members of water users association for sprinkling irrigation system, which amounted to about 5.6, The cultivation of maize, and potatoes in the water users' associations was exceeded compared to the different irrigation system in all the centers in the study sample. The second scenario aims beside minimizing the water needs of cropping pattern, increasing export crop areas such as onions, peanuts, potatoes, tomatoes and other vegetables as much as possible, assuming situation stability of foreign trade.  The results of the analysis of the statistical models in the second scenario showed that the total quantity of irrigation water available for the cropping pattern was about 41.483 billion m3, while 38,471, 38.912, 38.803 billion m3 were used for the statistical models respectively, indicating that the required water quantities decreased by 3.013, 2.572, 2.681 billion m3, with a change rate of about 7.26, 6.20, 6.46%, for statistical models, respectively. The net return of the water unit for the actual cropping pattern was about 1.634 LE/m3, while it reached about 1.773, 1.830, 1.833 LE/m3 for the statistical models respectively, which shows the increase in the net return of water unit by 0.139, 0.197, 0.199 LE/m3, with a change rate of about 8.53, 12.04, 12.21%, for statistical models respectively.  Crop rotations can be applied to the new lands using water savings including (wheat and maize), with an area ranging from 2048 to 2399 thousand feddans, and including (wheat and summer and nili vegetables), with an area ranging from 2941 to 3444 thousand acres, also including (maize, winter and nili vegetables), with an area ranging from 3432 to 4021 thousand feddans. With regard to the impact of reducing the area of water crops to water gap which reached about 20.9 billion m3, it decreased by about 2.879, 2.758, 2.800 billion m3, which make water gap decreased to about 18.02, 18.14, 18.10 billion m3, with change rate of about 3.77, 3.61, 3.66%, for statistical models respectively, while the results of the second scenario show decreased of about 3.013, 2.572, 2.681 billion m3, which make water gap decreased to about 17.89, 18.33, 18.22 billion m3, with change rate of about 3.94, 3.37 and 3.51% for statistical models respectively. The research recommends the following points: 1. Reduce the areas of rice, sugar cane and alfalfa to save a quantity of water ranging between 2.572 - 3.013 billion m3 of land within the valley. 2. Using of water savings resulting from reducing the areas of water crops to expand the cultivation of new land with strategic and monetary crops. 3. Sugar beet area can be expanded at least to the extent that it covers the shortage of sugar production caused by reducing the sugar cane area, then taking into account and study the effects resulting from that. 4. Modification of cropping patern structure to be in accordance with the local, regional, environmental situations that may affect current and future water availability.

The United Nations announced in 2016 was as international year for Legumes crops. As a part of sustainable food production, legumes are playing a vital role in Egypt for providing people with their needs from plant protein and amino acids. In general, Egypt suffers a gap between domestic production of legumes and consumption needs, particularly of Faba bean, and lentil. Thus, self sufficiency ratios reached 39% and 1.6% for both crops in 2014 respectively ([1]). Consequently, the imported amounts from both products were increasing during 1993 and 2014. So that the average of import value of Faba bean reached to LE 1.7 milliards alone, while lentil reached to LE 583.4 millions during 2010 and 2014, which represent about 66.2% and  22.3% respectively from  the average import value of legume crops.  Due to spread Balkiros injury in 2011, the cultivated area and domestic production of Faba bean has been significantly declined so that import value was increased. While, Faba bean domestic production represents about 78% of total legumes production, lentil represents only 1.3% as average of the period (1993-2014)([2]). The present paper aims to: (a) Identify the most important productivity and consumption indicators for leguminous crops in Egypt by using the equations of general time trend during the period (1993-2014). (b) Analyze statistical methods for predicting the most important economic indicators for legumes during the future period (2015-2024). ARIMA models were used to forecast production, consumption, and self-sufficiency after eliminating time series non-stationary and transferring it into stability or stationary series. This was done to be able to use PC-application econometric software package E-views 8 program. (c) Review, explain and interpret the results of ARIMA forecasting and the general time trend models as guidelines to draw agricultural production policy for legumes. ([1]) Ministry of Agriculture and land reclamation, economic affairs sector, the Central Administration of Agricultural Economics, Public Administration of agricultural economic resources, food balance sheets, various issues. ([2] ) Ministry of Agriculture and land reclamation, economic affairs sector, the Central Administration of Agricultural Economics, Foreign trade of agricultural exports and imports Bulletin, various issues.

Agriculture occupies an important position in the Egyptian economy. However, the agricultural sector is still undergoing many economic conditions and problems which have been hindered in the way of its development and modernization, which has directly or indirectly affected the role of the agriculture sector in economic development. Investment is one of the main means of development, The success of the development policy depends to a large extent on the volume of investments available and how they are distributed among different programs as well as the efficient use of those investments. Investment is one of the important tools in bringing about the structural change of the national economy. Through investment, technical progress plays its fundamental role. The rule is that any technical progress necessarily necessitates investment spending. If we look at economic growth in terms of work, investment projects contribute to increasing employment, Work productivity through increased capital intensity. This study deals with the current situation of national investment as well as agricultural investment in both public and private sectors in Egypt during the period 2000-2015, as well as the impact of the revolution of 25 January 2011 on the investment situation in Egypt. The time series was divided into three periods 2005), the second period (2006-2010) and the third period (2011-2015), the period of the revolution and beyond. The most important results are as follows: The general agricultural investment at current prices increases during the period of study (2000-2015). The revolution of 25 January also had a positive effect on the increase in general agricultural investment for the first and second periods.

A total of 75 pyogenic samples were collected from patients examinated for pyogenic infection in Sednawy hospital and Elmokhtaber laboratories. S. aureus isolated from pleural fluid out of five S. aureus (+ve coagulase, MSSA) exhibits resistant against all the concentration of Ciprofloxacin 0.5-20, Gentamycin 0.5- 5.0 µg/100µl and Amikacin 1 µg/100µl. The highest potent of phytoextracts either extracted by water or methanol was detected by clove comparing with mint, thyme, sage and garlic, whereas garlic essential oil gave completely abolish of S. aureus (P.F). The highest synergism was obtained in combination between the lowest inhibitory concentration of Gentamycin 10 µg/100µl  or Vancomycin 1 µg/100µl or Amikacin 2.5 µg/100µl with thyme Eso (1:3), which resulted to increase the efficacy by 4.4 or 1.5 or 1.6 respectively  comparing to recommended dose of the tested antibiotics alone. Increasing the concentration of garlic essential oil (GEso) from 10 up to 100 µl/well increment the efficacy of inhibition up to 10, 3.7 and 4.5- fold when standard dose of Gentamycin, Vancomycin and Amikacin were used individually against S. aureus P.F. The minimum bactericidal concentration of garlic essential oil was recorded at 2 µl/ml as it resulted to reduce the count to be 0.04%. Analysis of garlic essential oil by GC-MS dedicated six sulfur compounds represented 88.8644% of total detected compounds in garlic essential oil.

The study aimed to throw light on the current status of the area, productivity and production of citrus, orange and lemon in Syria, the development of the quantity and value of exports and imports, the export and import price of citrus, the development of the quantity and value of exports and exports price of the orange during the study period, the geographical distribution of Syrian exports of orange for the period (2007-2011), and standard samples for external demand on oranges. The foreign trade of citrus was in Syria the study showed that the production of citrus growing at a rate of about 38.12 thousand tons per year and the cultivated area of citrus growing at of about 1.35 thousand acres per year, the increase in the productivity of the hectare was not significant in any mathematical relation. The production of oranges increased by about 45% per year and the cultivated area of oranges increased by about 0.94 thousand acres per year, the increase in the productivity of the hectare was not substantiated in any mathematical relation. The production of lemons increased by about 6.73 thousand tons per year, growing at of about 0.28 thousand acres per year, the increase in the productivity of the hectare was not substantiated in any mathematical relation during the study period. The quantity of citrus exports increased by 24.9% per year, the value of citrus exports increased by 25.5% per year, the quantity of imports of citrus is increasing at a rate of about 19.5% annually, the value of imports of citrus is increasing at a rate of 24.9%, the quantity of exports of oranges is increasing at a rate of about 23.1% annually and the value of exports of oranges is increasing by 18.1%. The export price of oranges decreased by about $ 22.09 per year. In addition, the factors determining the average per Iraqi capita share of Syrian orange has been studied which indicated inverse relation between the dependent variable and the Syrian export price per kilogram in dollars, with an increase of 1% the average per Iraqi capita share of Syrian orange decreased by 2.45%. As well as a positive relation between the dependent variable and the average per Iraqi capita income in dollar and the export price of Turkey in dollars, by the increase of these factors of 1% the average per capita Iraqi quantity of Syrian orange increased by 1.98% and 1.37%, respectively. In addition, the factors determining the average per Jordanian capita share of Syrian oranges were calculated according to the export price of Syria in dollars. The model shows a positive relationship between the dependent variable and the export price of Lebanon in dollars. The average per Jordanian capita share of Syrian oranges was 2.88% and 0.75% respectively, which shown an inverse relation between the dependent variable and the export price of Syria in dollar, with an increase of 1%, the average per Jordanian capita share of Syrian orange decreased by 4.4%. The most important indicators of foreign trade of Syrian orange for the most important countries showed Russia in the first position in terms of the market share, which is about 96.1% of the total Syrian exports. It is clear that for political reasons between Syria and Russia. Then, Saudi Arabia and Kuwait came second with 1.7% of Syrian exports.

Salinity is a stress factor affecting the production of crop in many regions.  Calcium can reduce Na+ transport to shoots in rice. Two greenhouse experiments were conducted in Faculty of Agriculture, Cairo University, Egypt, during 2015 growing season of rice to evaluate the effect of different calcium concentrations on survival percent along with uptake of Na+ and Cl- ions by two varieties of rice (Oryza sativa L.) differing in salt-tolerance. The first experiment was undertaken to study the effect of different calcium concentrations on survival percent of IR28 (salt-sensitive) and Nona Bokra (Salt-tolerant) seedlings which were transferred to salinized nutrient solution containing 0.5% NaCl and a variable calcium concentrations at 4, 40, 100 and 200 ppm; plants were grown up to 40 days. The second experiment investigated the effect of different calcium concentrations on growth, uptake and transport of Na+ and Cl- ions in the two rice varieties differing in salt-tolerance. The seedlings were transferred to salinized nutrient solution containing 0.5% NaCl and calcium ion concentrations at two levels, 4 and 40 ppm. Plants were harvested at 0, 1, 3, 5 and 7 days from salinization. The results indicated that the salt-tolerant variety (Nona Bokra) survived for more than 40 days under exposure to 0.5% NaCl when calcium concentration of the culture solution ranged from 40 to 200 ppm Ca++. The low calcium ion concentration (4 ppm) depressed the growth of plants at 5 and 7 days after salinization.  In Nona Bokra, the shoot had less sodium and Cl than the root. This implies that the salt tolerance of Nona Bokra may be attributed to the restricted translocation of Na+ and Cl- from the root to the shoot. Sodium as well as cloride content in the shoot of IR28 was more than twice that of Nona Bokra.  An adequate amount of Ca+2 tended to lower the salt injury caused by high levels of salinity in rice plants. The effect of calcium ion on salt tolerance varied greatly between Nona Bokra and IR28 varieties.

Decline of grapevine due to soil borne fungi was surveyed during 2013- 2015 summer growing seasons at El-Fayoum, El-Gharbeia and El-Beheira governorates, Egypt, Syndromes of declined grapevine plants included growth retardant of shoot system and root-rot as well as decrease of grapevine fruit yield  quality. Isolation trails from root of declined trees of different grapevine cultivars i.e., superior, flame seedless, King robi and crimson was carried out. The most soil borne fungi associated with root-rotted grapevine were Fusarium oxysporum Schlechtend, Fusarium solani (Mart.) Sacc, Botryodiplodia theobromae, Rhizoctonia solaniKuhn and Macrophomina phaseolina(Tassi) Gold. Fusarium spp. are the main fungal associated with different infection types of declined root of grapevine either a singly or in combination with B. theobromae or R. solani as second infection type and third infection type with B. theobromae + R. solani. Under soil artificially infested with 5% (w/w) of each fungal isolates inocula of fourteen isolates obtained were varied for causing wilt and root-rot symptoms of grapevine trees and reducing growth parameters plant height, root length, root size, fresh and dry weight of shoot and root than the control. Botrydiplodia theobromae isolate No. (7)was the most caused root-rot and disease severity of shoot and root of grapevine plant(100%)  followed by Fusarium avenacum caused (87.5%) of root –rot and disease severity of shoot and root. Fouthermore, Fusarium avenacum isolate was the most fungal isolate in reducing growth parameters expect root length.  This is first record that Fusarium avenacum as a causal organism causing root rot disease of grapevine in Egypt.

Chlorella vulgaris belonging to Chlorophyta and Nannochloropsis  oculata belonging to Chrythophytawere used in the currentstudy to evaluate whether their successive indoor growth using industrial food waste (okara) as a growth medium enriched with organic carbon and nitrogenThe basic nutrient solutions were BG-II for Chlorella, while F2 was used for Nannochloropsis growth. Okara was used in four concentrations ( 25 , 50 , 75 and 100% )  verses to control and based on its initial nitrogen content. Original waste was diluted by 4 fold of tape water prior inoculation. The investigated parameters were dry weigh (g.l-1); total chlorophyll (mg.l-1) and total carotenoids (mg.l-1). Maximum dry weight of Chlorella was obtained with 25% of okara waste. As for Nannochloropsis, a slight increase was observed with all okara concentrations used. Lower okara concentration (25%) enhanced chlorophyll accumulation by Chlorella vulgaris, while higher concentration (100%) reached the maximum with Nannochloropsis oculata. Completely opposite pattern was observed with total carotene.

This research is concerned with the estimation of farmer’s demand for chemical fertilizers. The data were collected from a sample of farmers in two villages in Bani Sewaf Governorate in the summer of 2015.  Most farmers use two kinds of fertilizers; namely urea and superphosphates. Urea is provided to farmers in certain quotas at subsidized prices through the government controlled agricultural cooperatives. Farmers however find it necessary to rely on the free market to supplement the subsidized quotas of urea.  The research begins by estimating the Cobb-Douglas production functions for two field crops which are wheat and maize. Then the production functions coefficients are used to calculate the underlying cost functions. From the cost functions we were able to drive the conditional demand functions for chemical fertilizers with the help of Shephard’s lemma.   The estimates of all functions seem reasonable and consistent with economic theory. The elasticities of wheat production with respect to urea and superphosphates are 0.27 and 0.03 respectively. The wheat cost function is an increasing function in input prices and in output level. The conditional demand function for urea in wheat production is homogenous of degree zero in input prices; that is doubling the input prices will leave the demand for urea unchanged. Similar results for the maize crop were attained.  The maize production elasticities with respect to urea and superphosphates are 0.16 and 0.06 respectively. The results are statistically significant. The isoquant equation indicates that decreasing urea application by 0.42 sack can be compensated by increasing superphosphates application by one sack in order to keep the level of maize production at 18 ardab per feddan. The conditional demand function for urea reveals that an increase in the price of urea by EGP 5 would reduce the demand for urea by 0.78 sacks.