The green bean crop (Phaseolus vulgaris) is infested with many insects such as whiteflies (Bemisia tabaci). An investigation was carried out to study the insecticidal activity of whitefly (Bemisia tabaci), five pesticides were used, namely Thiamothoxam, Sulfoxaflor, Spirotetramat, Pymetrozine, and Flonicamid, and three commercial natural pesticides, namely Superrego, Topnine, and Bernastar. Pesticides and natural pesticides were sprayed during the two seasons of 2020 and 2021. The obtained results in terms of the reduction rate of the insects' number were as follows: The highest rate of reduction appeared in Thiamothoxam and Sulfoxaflor treatments, where it reached above 80%, while the other pesticides were in the range of 40% to 60%, and the lowest reduction rate was 34.33% and 36.00 % for Bernastar during season 2020 and 2021 respectively. When evaluating the toxicity of these pesticides and natural pesticides against honeybees (Apis mellifera), the pesticides did not reveal any toxicity to honeybees, except for Thiamothoxam, Sulfoxaflor, and Superrego The LC50 and LD50 values against honeybees were 0.2 ppm and 0.000005µg/one honeybee for Thiamothoxam, 4.5 ppm and 0.0001125 µg/one bee for Sulfoxaflor, and 0.95 ppm and 0.00002375 µg /one bee for Superego respectively.