The effectiveness of stress prevention with use of sedative remedy Xyla in a complex with preparations Ascorbic acid with glucose, Aesel and Katosal, which improve adaptation, was researched. Application of a complex of neurotropic and adaptogenic preparations before and after dehorning promoted softening of stressful influence, that in turn has positively affected the general condition of animals and intensity of growth. Comparative test of four schemes of preventive maintenance of negative consequences of the stress caused calf dehorning, has shown their high efficiency. However more expressed stimulating influence on intensity of metabolism, antioxidant status, natural resistance, adaptation to action of stresses-factors and rates of a body weight gain were rendered by the scheme with use of preparations Aesel, Ascorbic acid with glucose and Ksila

The diseases of newborn calves with a diarrhea syndrome are the most often registered. Application of the prebiotic preparations Biofon and Biofon-AIL to newborn calves daily with colostrum, milk or water in a dose of 20 ml within 20 days, allows to normalize intestinal digestion of an organism of young growth of calves at the expense of activization of microbiocenosis, stimulates metabolism and nonspecific resistance. Use of prebiotics allows to lower disease of young growth at Biofon application on 20%, Biofon-AIL - on 30% and to increase daily average additional weight gain of calves accordingly on 10,4% and 15,9%. Medical and preventive efficiency of application of prebiotic and probiotic preparations at enteritises at calves reaches 80-90%. Prebiotic preparations Biofon and Biofon-AIL make active nonspecific humoral immunity and exchange processes at newborn calves and can successfully be used for preventive maintenance and therapy of diseases of newborn calves with a diarrhea syndrome | У новорожденных телят наиболее часто регистрируются заболевания с диарейным синдромом. Применение пребиотических препаратов Биофон и Биофон АИЛ новорожденным телятам ежедневно с молозивом, молоком или водой в дозе 20 мл в течение 20 дней, позволяет нормализовать кишечное пищеварение организма молодняка за счет активизации микробиоценоза, стимулируют обмен веществ и неспецифическую резистентность. Использование пребиотиков позволяет снизить заболеваемость молодняка при применении биофона -на 20%, биофона-АИЛ - на 30% и увеличить среднесуточные привесы массы телят соответственно на 10,4% и 15,9%. Лечебная и профилактическая эффективность применения пребиотических и пробиотических препаратов при энтеритах у телят достигает 80-90%. Пребиотики Биофон и Биофон АИЛ активизируют неспецифический гуморальный иммунитет и обменные процессы у новорожденных телят и могут успешно использоваться для профилактики и терапии заболеваний новорожденных телят с диарейным синдромом

The modern technology applied on poultry enterprises of the Republic of Belarus made provision for high concentration of poultry population density at the comparatively small housing areas of integrated poultry farms which caused the deterioration of sanitary conditions in poultry houses, especially by the end of the growing period. Broiler chickens grown under such conditions were constantly experiencing the microbe stress which eventually caused the heightened culling and poultry losses caused by different diseases caused both by pathogenic and conditionally pathogenic microflora. For the current disinfection in presence of poultry it was proposed to use sprayings with malic and succinic acids, which made it possible to realize not only the air sanation in poultry houses, but also increase broiler chicken viability. The highest bactericidal activity of apple acid aerosol against air microflora was stated within 3 hours after carrying out indoors treatment. After disinfection the general microbic air contamination decreased in 2-10 times, quantity of microorganisms of colimorphic groups and staphilococcus in 1,4-1,75 and 2-10 times, respectively, in comparison with the original air values realized before air treatment in poultry houses. In the following, there was stated the gradual increase of a level of microbic air contamination within 24 hours. The best effect of the preparation was stated against Staphylococcus. Thus, the quantity of Staphylococcus in air decreased in 10 times in comparison with initial data

The increasing number of diseases with urogenital chlamydiosis became a serious problem for the modern veterinary science. The importance of urogenital clamidiosis in the infectious pathology of animals was presented by the direct multifocal affect of urogenital system and after-effects of a disease influencing the reproductive function, as well as the potential hazard of its transformation into a source of chlamydia infections of other localization. In the conditions of the Republic of Belarus the chlamydial endometritis of cattle in the majority of cases was associated with Staphylococcus aureus in 25,7% of cows. Chlamydial endometritis of cows was usually preceded by: embryotocia (9,9%), pathological calving (4,4%), retention of placenta (14,8%), subinvolution of uterus (27,1%). The biochemical tests in trial group showed the 23% decrease of carotin on twofold decrease vitamin A. In course of the immunologic studies it was established, that dilution of A class immunoglobulins was on 31% higher in animals of a trial group in comparison with the control group. The level of IgG immunoglobulin G and immunoglobulin M slightly differed between groups

The influence of various light regimes on productive indices of broiler chickens cultivation of СОВВ cross taking into consideration the course of some exchange processes was studied in the conditions of the Republic of Belarus. There were formed 4 groups of one-day-old chickens with the approximately identical body weight. For the chickens of a control group there was used the standard for Belarusian poultry farms light regime, i.e. 23 hours of light and 1 hour of darkness (23L:1D), in three experimental groups there were used the following light regimes: first - (3L:1D) х 6, second - (2L:1D) х 8, third - (1L:1D) х 12. The predetermined conditions were set by means of filament lamps with 15 W capacity. Throughout the whole experiment there was realized the identical feeding level for all groups: during the first growing period (1-30 days) chickens were fed with mixed fodder PK 5B containing 22% of crude protein and 296,6 kcal of exchange energy, during second period (31-42 days) - PC 6B containing 20% of crude protein and 332,2 kcal. In the applied mixed fodders there was used enzyme Rovabio. Research results showed that metabolic processes occurring in chicken body in the majority opf cases depended on application of various light regimes. Interchange of light and darkness periods (3 hours of light and 1 hour of darkness) х 6 at light exposure in 15 lk rendered the positive effect on the activity of endocrine systems of chickens of СОВВ crosses. In mentioned above group of chickens the hormones directed their metabolic processes towards increasing the productive indices, namely: daily average gain of chickens of the first group was authentically higher than the same index in the second and the third groups on 13,6% and 17,9%, respectively

In the conditions of biogeochemical zone of the Republic of Belarus the most important role in mineral metabolism is played by such major mineral elements as calcium, magnesium, phosphorus, potassium and trace elements - cobalt, cupper, iron, iodine, zinc, manganese, and selenium. Based on the above there was determined the interrelation between the content of these minerals in fodder and blood of milking and dry pregnant cows. As a result of realized study it was found out that the content of major mineral elements and trace elements in fodder did not always correspond to their level in blood. In the conditions of insufficient supply of Ca, F, Mg, K, Fe, Си and Co in cow diets, the level of potassium in blood was lower standard and the other analysed minerals were within the standard limits. There was stated the direct correlation relationship between the level of some biochemical indices and content of mineral substances in cow diets. Positive correlation was stated between the content of calcium and magnesium and cholesterin level in blood

In animal feeding technology much attention is given to application of biologically active substances for metabolism stimulation. One of such biologically active substances is carnitine, an anabolic preparation of nonhormonal nature, cofactor in system of oxidation of fat acids. It participates in processes of acetylation at oxidation of fat acids together with acyl-CoA and other enzymes, promotes carrying over of cytoplasmatic Coa-derivatives of fat acids inside mitochondrions. It increases absorption speed from a digestive path of nutrients of forage, raises use of fat acids for the power purposes. Under its influence synthesis of triglycerides decreases and synthesis of phospho-lipids increases. Carnitine also protects cells against toxic accumulation of components of acyl-CoA of endogenic or exogenous origins, such as acylic groups of carnitine ethers which then can pass into liver for dissimilation or in kidneys for allocation in urine. Carnitine synthesis satisfies body requirements, but in the conditions of a hightened stress, high productivity, as well as in the conditions of lowered carnitine content in forage or in the conditions of the increased content of fats it should be applied as additive to diet. As a result of the realized study it was established, that the optimal quantity of carnitine application in diets for stores husbandry and fattening is dose of 50 g/t of mixed fodders. Application of carnitine in an optimum dose renders the positive impact on animal organism, promotes the increasing average daily weight gain on 5,1% (Р less than 0,001). Application of carnitine in diets of swine stores increases a slaughter yield on 2,1%, meat content per carcass - on 2,3%, a loin eye area - on 8,8%. Carnitine application in a dose 50 g/t of mixed fodders makes it possible to receive the additional profit at a rate of 4,57 USD per 1 head

The data about influence of the developed home-produced inactivated vaccine against pasteurellosis of fur animals on blood, biochemical, immunity indicators at mink are cited. It is established, that application of the given preparation conducts to formation of the necessary immune answer. The developed domestic inactivated vaccine against pasteurellosis of fur animals is a harmless and areactogenic preparation. This vaccine does not render negative action on hematological and biochemical indicators of mink blood. They are identical to indicators in control group of fur animals. Immunization with this vaccine stimulates cellular and humoral immunity factors that testifies to formation of the proof immune answer | Приведены данные о влиянии разработанной отечественной инактивированной вакцины против пастереллеза пушных зверей на гематологические, биохимические, иммунологические показатели норок. Установлено, что применение данного препарата ведет к формированию необходимого иммунного ответа. Разработанная отечественная инактивированная вакцина против пастереллеза пушных зверей является безвредным и ареактогенным препаратом. Инактивированная вакцина против пастереллеза пушных зверей не оказывает отрицательного действия на гематологические и биохимические показатели крови норок. Они идентичны показателям в контрольной группе пушных зверей. Иммунизация инактивированной вакциной против пастереллеза пушных зверей стимулирует клеточные и гуморальные факторы иммунитета, что свидетельствует о формировании стойкого иммунного ответа

There was studied the feature of hematological and biochemical blood indicators of rats at action of acute ionising radiation against acute stress influences. Results of research of hematological and biochemical blood indicators of rats developing under influence of stress and radiating factors are presented. It is established, that on 4 days twenty-four-hour period after the influence of pointed ionizing radiation against a background of pointed stress impact some changes become evident. They appear in reducing of total number of leucocytes, haemoglobin, hematocrit and general albumen, and also in increase of such ferment activity as lactate dehydrogenase, creatine phosphokinase, aspartate aminotransferase, alanine aminotransferase. | Целью исследования является изучение особенности гематологических и биохимических показателей крови крыс при действии острого ионизирующего излучения на фоне острого стрессорного воздействия. Представлены результаты исследования гематологических и биохимических показателей крови крыс, развивающихся под влиянием стрессорного и радиационного факторов. Установлено, что на 4 сутки после действия острого ионизирующего излучения на фоне острого стрессорного воздействия отмечаются изменения, выражающиеся в снижении общего количества лейкоцитов, гемоглобина, гематокрита и общего белка, а также увеличении активности ферментов лактатдегидрогеназы, креатинфосфокиназы, аспартатаминотрансферазы и аланинаминотрансферазы.

The metabolism disorders of subclinical nature in pregnant cows are characterized with intoxication processes development, swift of acid - alkaline balance and cytolyses activation. The listed factors promote occurrence of neonatal pathology - congenital calve hypotrophy. Degree of display of the given pathology depends on severity level of the metabolism disorders in pregnant dry cows. In the tabular form results of the spent haemotological and biochemical research are presented: haemotological and biochemical indicators of blood pregnant dry cows for the 14-21 day prior to assumed calving; haemotological, biochemical and immunologic indicators of blood of newborn calves with various degree of antenatal hypotrophy. | Нарушение обмена веществ субклинической природы у стельных сухостойных коров характеризуется развитием интоксикационных процессов, сдвигом кислотно-щелочного равновесия и активацией цитолиза. Перечисленные факторы способствуют возникновению неонатальной патологии - врожденной гипотрофии телят. Степень проявления данной патологии зависит от степени тяжести нарушения обмена веществ у стельных сухостойных коров. В табличной форме представлены результаты проведенных гематологических и биохимических исследований: гематологические и биохимические показатели крови стельных сухостойных коров за 14-21 день до предполагаемого отела; гематологические, биохимические и иммунологические показатели крови новорожденных телят с различной степенью антенатального недоразвития.