A pregnant Saanen doe aging 1.5-year and weighing 40 kg was presented to the Large Animal Unit of Universiti Putra Malaysia Veterinary Hospital with history of inability to stand up. Transabdominal ultrasonography of the animal revealed two live fetuses at late pregnancy. Blood examination revealed decreased lymphocyte numbers, and increased monocytes count. Biochemical analyses showed marked decrease in glucose level and elevated level of aspartate aminotransferase (AST) and creatine kinase (CK). The goat was administered with 200 mL 20% Dextrose (G-20), NaCl solution (at 1.3 mL/animal), Flunixine meglumine (at 2.2 mg/kg bwt), and Vitavet multivitamin (at 1 mL/10 kg bwt). The prognosis of the case was grave, and the goat was sacrificed in order to save the fetuses. However, the fetuses were died within 10 min. Necropsy of the doe showed pale, yellow and friable liver and congested lungs, while histopathological evaluation of the liver showed diffuse hepatic lipidosis. Pregnancy toxemia in doe can be prevented by providing proper nutrition.

The objective of the present study was to monitor the hypolipidemic and hypocholesterolemic effects of propolis in rats fed high cholesterol diet. The rats (n=32) were divided into four equal groups. The rats of group 1 (control) were fed basal diet, whereas rats of group 2 were fed basal diet mixed with cholesterol (1%). The rats of group 3 and 4 were fed high cholesterol diet (1%) mixed with propolis powder 1 and 2%, respectively. Hematological parameters were comparable among all groups. Cholesterol, triacylglycerol and ALT activities were increased significantly in rat fed high cholesterol diet as compared to control. Inclusion of propolis in high cholesterol diets reduced these parameters in serum. Hematological and biochemical findings were supported by histopathological analysis of liver tissues. Conclusively, 1% propolis was found as safe and enough to induce beneficial hypolipidemic and hypocholesterolemic effects in serum of rats fed high cholesterol diet.

This study was conducted to assess the effect of white mangrove (Langucularia racemosa) leaves (as feed additive) on some serum biochemistry in adult female rabbits. Twenty four mature female rabbits (does) were randomly allocated to four equal groups (Group A, B, C, and D) in a Randomized Complete Block Design (RCBD). Group A was served with control diet, while the does of Group B, C and D were fed growers mash mixed with the additive dosed at 70 g, 80 g, and 90 g/kg of feed, respectively. Blood samples were collected from the animals for biochemical analysis at the end of the 12-week study. Sections of the liver were collected from same does for histological investigations. The results of the serum biochemistry showed no significant difference (p>0.05) in the values of Aspartate Transaminase (AST), while significant differences (p<0.05) were observed in the values of Alanine Transaminase (ALT), and Alkaline phosphatase (ALP). The histology of the liver was normal. It was concluded that the test ingredient (L. racemosa) was safe to be used in the diet of female rabbit dosed at 70-90g/kg feed since the enzyme levels remained within normal range of healthy rabbit.