Effects of the following treatments on abomasal and duodenal myoelectric activity in yearling cattle were studied: 2 ml of 0.9% sodium chloride solution (NACL); 0.07 mg of bethanechol (BET)/kg of body weight; 0.1 mg of metoclopramide (MET)/kg; and 0.07 mg of bethanechol and 0.1 mg of metoclopramide (BETMET)/kg. All treatments were administered SC during the early part of phase I of the migrating myoelectric complex Myoelectric signals were recorded for 4 hours after administration of the treatments from 1 electrode in the antrum and 3 electrodes in the duodenum. For the antral spike rate (ASR), there was no significant difference among treatments during the first hour, but the ASR was significantly (P < 0.05) greater during hours 2 to 4 after treatment with BETMET, compared with ASR for MET alone. The duodenal spike rate (DSR) was significantly (P < 0.05) greater during the first hour after administration of BETMET than after the other treatments. After administration of BET, DSR was significantly (P < 0.05) greater than after MET or NACL. There was no difference in DSR after MET, compared with DSR after NACL. There was no significant difference in DSR among treatments during the second and third hours. The total antegrade propagating spike (TAPS) count was greater after administration of BETMET in all hours, compared with the other treatments. The ratio of TAPS to total spikes on the orad-most duodenal electrode was significantly (P < 0.05) greater after BETMET during hours 1 and 2.

Studies of morphological and morphometrical particularities of rennet of newborn calves with different degree of antenatal hypotrophy were realized in the conditions of the Republic of Belarus. Scientific-and-production researches were spent in 2007 - 2008 on the basis of agricultural production co-operative Dembrovo (Shchuchinskij district, Grodno area, Belarus), agricultural production co-operative Okhovo (Pinsk district, Brest region, Belarus) and research laboratory of Grodno State Agrarian University (Belarus). For an estimation of morphofunctional maturities there were used 165 1-day old calves. Research results showed that in the studied calves the basic indexes of glanderous apparatus of rennet proved the different degree of morphofunctional immaturity. In calves with hypertrophy in the first days after birth there stated an active morphogenesis of all cytological components of rennet

There was studied the ulcerous changes in a rennet stomach paries. The analysis of literary data has allowed to choose a way of reproduction of rennet stomach ulcer at calves by means of haemodynamic frustration of rennet stomach site. During experiment has been reproduced ulcer abomasit at 13 heifers. In the course of work the young growth of black-motley breed at the age of 1-2 months has been involved. Before operation to calves neuromuscular relaxant Rometar intramuscularly was entered. Then alcoholic narcosis on M.V.Plakhotin intravenously was entered. Belly cavity on a white line of stomach, receding from chondroxiphoid cartilage on 4-5 cm, was opened. A cut in length 10-12 cm was done. Through the formed aperture rennet stomach was taken, then on the big curvature gastroepiploic artery was found, into which by medical syringe through an insulinic needle was entered warmed up to 38 deg C the 8-% solution of sulfosalicylic acid in a dose of 5 ml. Changes from a serous cover of rennet stomach observed at once after introduction of acid solution. At first on an artery course rough spastic reductions of rennet stomach muscles have been noticed. After that, in the same place, there was anaemia of serous cover, then, stagnant hyperaemia. For the control of results in 3-5 weeks made the compelled slaughter of calves with the diagnostic purpose and found out rennet stomach ulcers of various size. Result of the given work is that the given method gives the chance to reproduce haemodynamic rennet stomach ulcer at calves of any age by means of 8% solution of sulfosalicylic acid. Thus, the experimental model of rennet stomach ulcer at the calves, caused by introduction of 8% solution of sulfosalicylic acid, is in the main similar to spontaneous disease. | Целью экспериментальной работы явилось изучение ульцерозных изменений в стенке сычуга. Анализ литературных данных позволил выбрать способ воспроизведения язвы сычуга у телят посредством гемодинамических расстройств участка сычуга. Во время эксперимента был воспроизведен язвенный абомазит у 13 телочек. В процессе работы был задействован молодняк крупного рогатого скота черно-пестрой породы в возрасте 1-2 месяцев. Перед операцией телятам вводили внутримышечно миорелаксант Рометар. Затем вводили внутривенно алкогольный наркоз по M.B. Плахотину. Брюшную полость вскрывали по белой линии живота, отступая от мечевидного хряща на 4-5 см. Делали разрез длиной 10-12 см. Через образовавшееся отверстие извлекали сычуг, затем находили на большой кривизне желудочно-сальниковую артерию, в которую шприцом через инсулиновую иглу вводили подогретый до 38 deg С 8-процентный раствор сульфосалициловой кислоты в дозе 5 мл. Изменения со стороны серозной оболочки сычуга наблюдали сразу же после введения раствора кислоты. Сначала по ходу артерии были замечены бурные спастические сокращения мышц сычуга. После этого, там же, возникала анемия серозной оболочки, затем, застойная гиперемия. Для контроля результатов через 3-5 недель производили вынужденный убой телят с диагностической целью и обнаруживали язвы сычуга различной величины. Результатом данной работы является то, что данный метод дает возможность воспроизводить гемодинамическую язву сычуга у телят любого возраста при помощи 8-процентного раствора сульфосалициловой кислоты. Таким образом, экспериментальная модель язвы сычуга у телят, вызванная введением 8-процентного раствора сульфосалициловой кислоты, в основных чертах сходна со спонтанным заболеванием.

In the conditions of the Republic of Belarus there was realized an experimental study of a new method treatment of calves diseased with abomasoenteritis by means of application of a preparation Ranitidin. As a result of realized research it was established that the preparation had an expressed therapeutic activity. Inclusion of Ranitidin preparation into the complex therapeutic regimen of calves sick with abomasoenteritis with the enteral feeding once in day in a dose of 0,15 g promoted the reduction of duration and decrease in severity of the disease. There were presented the results of biochemical blood indicators in trial and control groups of calves, haematologic indices in trial and control groups of calves prior to the beginning of experiment and in the end of the test.

Realized review of research works showed that pathologic behavior of ulcerous abomasitis of calves, its preventive maintenance and treatment, as well as the functional status of liver of heart of sick calves require more thorough analysis in the conditions of the Republic of Belarus. Research results proved the perspective direction of experimental investigation of ulcerous abomasitis of calves by means of ulceration of mucous membranes of fundic portion of fourth stomach y means of derangement of circulatory dynamics of organ portions. The proposed experimental model made it possible to obtain animals with pathology similar to the main clinical, biochemical and morphofunctional parameters with such unprompted pathology. Results of realized experiment on reconstitution of ulcerous abomasitis at 13 calves were presented. Indexes of total clinical blood analysis at different stages of experiment, white blood cell differential, biochemical blood indexes, and indexes of abomasal content of experimental calves were presented