Balb/c mice were used for investigating, the ability of the fungus (..'lada.s'porr‘zun sp. To infect the animal organs. Livers and kidneys of the animals were fixed and liistopathologieally examined after injecting the animal with ftlllgal spores. The study showed that the fungus (.'lado.s-porfzmz sp. is able to infect the animal organs . Fungal mycclia was observed among tisstie cells in addition to many histological changes such as cell (lcgcneration, necrosis. ecmgestion and bleeding.

Difierent co1icc1)tratio1) ol'rit;1(npin and Ciprotlox'tcin ~vere tested I'or their activities in iil>(~ a Keywords rifampin --- Leishmanicidal --- CL.