Investigation of influence of water improved by potassium permanganate solution on welfare and productivity of piglets was realized in the conditions of swine breeding complex in the Republic of Belarus. In the experiment there were used 2 groups of 30-day old piglets. In course of 75 days of experiment the running water of pig complex was used for watering of piglets of control group. Piglets from the experimental group were given water with addition of 0,1% solution of potassium permanganate. Analysis of obtained results showed that water with potassium permanganate promoted the increasing of natural resistance of piglets. At the same time there was stated the increasing of lysozyme and bacterial activityin blood serum. Application of improved water promoted the increasing hemoglobin on 4,8-4,5%, erythrocytes - on 2,9-4,2% in comparison with control. Content of total protein increased on 2,2-2,8% in the experimental groups, lisozyme activity - 6,9-7,0% and bacterial activity - on 5-6,9%. Application of improved water did not influence the glucose and potassium concentration in blood. In the experimental group there was stated the increased lipid concentration on 3,1-6%, cholesterol - on 4,4-6,3%, potassium level - on 2,5-4,5%, phosphorus - on 0,7-5,3%, sodium - on 1,4-3,8%. Application of water with КMnО4 increased average daily weight gain on 5,2-4,2%

Study of peculiar features of protein metabolism of healthy colts in the first three months of life was realized in the conditions of the Republic of Belarus. Research results showed that there was a tendency of increasing of hemoglobin concentration up to 150,270+/- 4,73 g/l, number of total protein of blood serum – up to 60,33 +/- 1,33 g/l, and the decreasing of uric acid up to 97,33 +/- 10,72 micromole /l. Quantity of beta-1 and alpha globulin fractions of serum protein fluctuated a little – from 10,78 +/- 3,69% up to 8,44 +/- 1,24% and from 25,12 +/- 4,84% up to 22,06 +/- 4,93%, respectively. The most essential changes of protein metabolism were stated at two month old colts, which had urea concentration of 5,25 +/- 0,23 micromole/l, alanine aminotransferase activity – 66,92 +/- 3,16 units/l, creatine content increased up to 77,37 +/- 5,83 micromole /l; and there was the lowering of aspartate transaminase level up t159,5 +/- 8,1units/l. There was stated the lowering of albumin quantity up to 32,07 +/- 2,19%, and increasing of alpha-1, alpha2- and beta2- globulin fractions up to 7,52 +/- 1,23%, 14,98 +/- 1,41%, 11,82 +/- 1,04%, respectively. At the age of three months the quantity of urea and creatinine in blood serum of colts remained at the same level, alanine aminotransferase activity decreased on 21,56%, and aspartate transaminase increased up to 204,33 +/- 10,37 units/l. At this period the quantity of albumin fractions was 44,56 +/- 6,59%., concentration of alpha-1, alpha2- and beta2- globulins decreased on 10,64%, 30,04% and 34,52%, respectively

Realized review of research works showed that pathologic behavior of ulcerous abomasitis of calves, its preventive maintenance and treatment, as well as the functional status of liver of heart of sick calves require more thorough analysis in the conditions of the Republic of Belarus. Research results proved the perspective direction of experimental investigation of ulcerous abomasitis of calves by means of ulceration of mucous membranes of fundic portion of fourth stomach y means of derangement of circulatory dynamics of organ portions. The proposed experimental model made it possible to obtain animals with pathology similar to the main clinical, biochemical and morphofunctional parameters with such unprompted pathology. Results of realized experiment on reconstitution of ulcerous abomasitis at 13 calves were presented. Indexes of total clinical blood analysis at different stages of experiment, white blood cell differential, biochemical blood indexes, and indexes of abomasal content of experimental calves were presented

Searching for new, effective and safe methods of treatment of hookworm disease (ancylostomatidosis) of dogs caused by Ancylostoma caninum and Uncinaria stenocephala was realized in the conditions of the Republic of Belarus on the basis of studying of spices composition and dissemination of Ankilostomatidae, age-specific and seasonal disease dynamics, testing of medical and preventive preparations Univerm and Fenbendazol. In the Republic of Belarus Ancylostoma caninum was stated 4,2% of studied cases and Uncinaria stenocephala – in 14,3%. The maximum intensity of the invasion was stated in summer and autumn periods: in cases of individual keeping – 19,4%; in cases of group keeping the disease transformed into enzootic form with 66,7% affect. In winter period there was the lowest invasion – up to 1,4%. The preparation Univerm administrated twofold with feed in dose of 0,1 mg/kg with 24 hours interval proved to be highly effective therapeutic agent with extensefficiency100%. Anthelmintic Fenbendazol administrated once with feed in dose of 0,005 g/kg proved to be highly effective with extensefficiency 80% and intensefficiency 98,84%. Hematological indexes of sick dogs showed the evidence of erythropenia (4,30-4,80 x 10E12/l), hemoglobinemia (113-119 g/l) and eosinophilia (up to 11%), as well as the increased quantity of leukocytes on 5,46% - 23,61 %, and the lowered quantity of lymphocytes on 15,84 % in comparison with healthy animals indexes

In the conditions of the Republic of Belarus there was realized a study of age-specific features of level of erythrocytes, haemoglobin in blood, activity of aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alkaline phosphatase, as well as concentration of calcium, phosphorous, magnesium and ferrum in blood serum of suckling colts in the first 6 months of life. In the studied animals there was stated increased levels, haemoglobin and ferrum concentration in blood, but during the 6th month of life the same indexes decreased considerably. The most considerable changes оf blood serum enzymatic activities occurred at the age of 2 and 6 months. Thus, during the 2nd month of life a raise in ALAT, LDH activity, calcium and phosphorus concentration was noticed. At the age of 6 months ALAT and ASAT levels increased, and LDH activity, magnesium and phosphorus concentration decreased. During the first 6 months of life the ALP activity was on a high level and underwent no reliable changes. As the research showed, blood serum enzymatic activity and concentration of calcium, phosphorus, magnesium and ferrum depended on colt age and change at the process of growth and development of animals.

An effort to demonstrate the mechanism of homeostatic alteration of high-producing cows at the period of increasing milking capacity and peculiar features of its changing in the conditions of introduction into cattle diets of carbohydrate containing and carbohydrate compensative additives was realized in the conditions of the Republic of Belarus. In course of the experiment there were used white-and-black breed cows of 3-4 lactations with body weight of 700 kg and milk yield over the last lactation of 7000-8000 kg of milk. Experimental cows in two weeks before the supposed calving were administrated with 50 ml of propylene glycol, 6 g of niacin and 50 ml of glycerin; and in course of 60 days after calving the administration of the additives was realized in doses of 125 ml; 6 g; 50 ml, respectively. Research results showed that application of mentioned above additives rendered the positive effect on cow liver that was proved by the improved hemic function of experimental cows: increasing of quantity of erythrocytes, hemoglobin, and hematocrit