The spectrum of acaricides changes continuously and improves. At the same time, big attention is given to research of new, more effective preparations meeting modern requirements. Research on studying the efficiency of Akaribil preparation against swine sarcoptosis (Sarcoptidae) was realized in the conditions of swine breeding farm in the Republic of Belarus. The preparation possesses high insect-acaricidal activity. In the conditions of the preparation storage and repeated opening of a ware in the course of tests there were stated no changes in drug smell or color. The scheme of the preparation application is applied in industrial production technology. It possesses anti-inflammatory properties, antiseptic stimulating healing of skin damages, does not irritate integuments, renders weak irritating effect on mucous membranes of eyes. In recommended doses Akaribil does not cause any adverse effects and complicating disease. There were stated no contraindications to preparation application. High therapeutic efficiency against arachnoentomosis was proved. Application the preparation made it possible not only to reduce disease incidence and animal death, but also to facilitate the severity of scabietic diseases. As a result of realized research it was established that efficiency of Akaribil against swine sarcoptosis was 100%.

In the conditions of the Republic of Belarus there was studied the application of sodium chloride obtained by electrolysis method on Akvamed installation in a complex of activities for the preventive measures of animal helminthoses. Electrochemical activation of aqueous solution of sodium chloride proved to be a progressive and rational technology which made it possible to substantially reduce the material costs and power consumption for the development of highly efficient and ecologically safe disinvasion solution. Application of sodium chloride solution with the minimal content of available chlorine of 3,0 g/l provided the death of 94-95% of Taeniidae eggs in course of 30 minutes after applicated of the preparation on the treated surface. The proposed method can be recommended as the most efficient and economically effective for the disinvasion of external environment.

In the conditions of the Republic of Belarus there was developed a concept for differentiation of eimeria and helminthes using a system of identification indexes as mathematical expressions of morphometric correlations of eimeria oocystae and helminth eggs morphology. There was developed a method for identification eimeria species on the basis of two-dimensional mathematical analysis of oocysts using a new identification index which represented a duplication proportion of contour perimeter to surface area of an oocyst.

General characteristic of parasitologic situation at the exclusion zone, some aspects of new conditions influence on separate systematic groups of mammal parasites Polesye State Radiation and Nature Reserve of the Republic of Belarus were presented. Research of helminth fauna and helminthological situation was realized by an example of 1 European bison, 7 mooses, 20 roe deers, 26 boars, 25 wolves, 50 racoon dogs, 6 foxes and 3 beavers. Scatoscopy of the animal excrements was realized by Kalantaryan method with saturated solution of sodium saltpeter, Berman method. Research results revealed 66 helminth species belonging to 4 classes and 34 families. There were found 10 parasite species at bison, 16 – at mosses, 17 – at roe deers, 16 – at boars, 8 – at deers, 23 – at wolves, 13 – at raccoon dogs, 13 – at foxes, 9 – at badgers and 1 – at beavers. Analyze of helminthofauna of the analyzed area showed that the nature reserve had its own helminthes complex. A lot of stated helminth species were parasites with a wide range of hosts, including domestic animals, and cattle. Wolves, foxes and raccoon dogs were hosts of some custodies invasions. Carnivorous animals and murine rodents were hosts of trichinosis invasion, which was stated at 41,2 % of raccoon dogs, 33,3 % of foxes and 16,7 % of wolves. Also trichinas were stated at bank vole (1,3%), yellow-necked mouse (2,7%), and house mouse (16,6%)

On the basis of analysis of literary sources and realized studies there was realized an evaluation of the degree of losses caused by ruminant monieziasis in the conditions of modern agricultural production in the Republic of Belarus; the strategy of medical and preventive measures was presented. In course of studies there were analyzed sheep and cattle of different classes bred in farm holding of Belarus and imported from abroad, as well as different anthelmintic agents. Studying of antihelminthefficiency was tested on lambs with body weight 20 kg. Lambs were infested with moniezia (Moniezia expansa). Analysis of anthelmintic agent Alverm efficiency was realized by the example on infested heifers. Albazen was administrated once in dose of 0,8 mg/1 kg. Prazikvantel was administrated once in dose of 5,0 mg/1kg. Alverm was administrated once in dose of 80,0 mg/1 kg. Research results showed 100% extencefficiency and intencefficiency of albazen and prazikvantel. Alverm administrated once in dose of 80,0 mg/1 kg gly had 100 % 100 % extencefficiency and intencefficiency

Development of scientifically based activities for rehabilitation of waterfowl (ducks) against helminthoses on the territory of the Republic of Belarus was realized. In course of the study there were analyzed fauna of helminthes and revelation of the main ways of their circulation in environment conditions; expansion and species composition of mollusks of Belarusian Poozerye; determination of species composition of metacercaria revealed in mollusks. In course of determination of intermediate and additional hosts of helminth infestation of ducks it was noted that the main carriers of larval stages of helminthes in ducks were the following species of frash-water mollusks: Vivaparus contectus; Vivaparus vivaparus; Galba palustris; Radix ovata; Radix auricularia; Sphaerium subsolidum; Bithynia tentaculata; Planorbis carinatus; Planorbis planorbis; Coretus corneus. In the studied samples there were revealed metacercaria of Echinostoma revolutum; Hypoderaeum conoideum; Cataropis verrucosa; Echinostoma dietsi. Assumption that some representatives of molluscum (Viviparus contectus; Viviparus viviparus; Planorbis planorbis) were the transport hosts for echinostomiasis was not proved.

Determination of influence of long acting antihelminthics (Aversictini boluses and boluses with albendazole) and influence of usual antihelminthics (farmatsin, alverm, fenbendavet) on first stomachanimal digestion, as well as on quantity and quality composition of microflora and microfauna in first stomach and large bowel was realized in the conditions of the Republic of Belarus. In course of the experiment there were used 6 groups of calves infested with helminths (Neoascaris vitulorum, Strongylata sp.). Research result showed that different antihelminth preparations to a greater or lesser degree rendered negative influenced on quantity and quality composition of microorganisms in first stomach and large bowel of cattle. Alverm and boluses with albendazole rendered the least influence on microflora and microfauna that could be explained by low toxicity of active substance (albendazole) of the above preparations. Aversictini boluses, fenbendavet, and farmastin changed the composition of microorganisms. It could be explained by high toxicity of preparations containing aversictini which rendered influence not only of gastro-intestinal tract but also on the whole organism. Active ingredient of mentioned above preparations (Aversektin C), being the product of microbial synthesis, rendered the antagonist action on the normal microflora of digestive tract. Negative influence of fenbendavet was caused by the chemical composition of the preparation and neurotoxic action of fenbendazol