An experiment was conducted on 100 day in old broiler chicks to study the immunosuppressive potential of Argemone mexicana seeds toxicity. Toxicity was induced by administrating crushed Argemone seeds @ 5, 10,20 and 30 grams per Kg of feed in treatment groups Tl, T2, T3 and T4 respectively whereas the Control group was maintained on the normal feed. The birds in the treatment groups showed the symptoms like dullness, depression and ruffled feathers. The body weight gain (BWG) was poor in comparison to control. The lymphoid organ to body weight ratio, HI titers and percentage of active macrophage were found significantly reduced. The histopathological lesions revealed marked lymphoid depletion indicaive of immunosuppressive potential ofArgemone seeds.

The level of antibody by ELISA,immunsosuppressive effect baes on the response of birds to Newcastle disease vaccination and damage to bursa of Fabricius by IBD vaccination were studied. The efficacy of six different IBD vaccination schedules were studied using intermediate and intermediate plus strains of vaccines either alone or in combination. In vaccinated groups, the sero-conversion of the vaccine virus was noticed during fourth week, reaching to the peak between eight to twelve weeks of age in different groups. Afterwards, there was a gradual decrease in the titres, by the end of 20th week (maximum period tested). There was no significant difference in the titres of different treatment groups. However, all the groups showed titres above protective level during the entire period of study. There was significant difference in bursa body weight (B-BW) ratios of vaccinated groups in comparison with control group. Histopathological studies of bursal sections revealed depletion of lymphoid follicles, presence of cystic spaces, edema and hemorrhages. The birds vaccinated with hot strain of IBD vaccine showed metaplastic changes, presence of foam cells with pronounced interfollicular fibrosis. The bursal scores were maximum in the groups vaccinated with hot strains of IBD vaccines.

A study was conducted in buffaloes suffering with horn affections .The physiological and haematological parameters were within the normal limits in all the horn affections, but the plasma cortisol and C-reactive protein were more than the normal levels in all the horn affections for initial periods. A radiological sign like increased radio-opacity was noticed in the septic horn cases. Microscopic examination of biopsy samples of horn and skin following amputation revealed normal histology except in horn cancer where squamous cell nests and mitotic figures in the squamous cells were observed.

A one and half year old heifer was presented with a hard mass hanging from brisket region. The mass was oval shaped, 10 x15 cm in size, pedunculated with the base at the level of carpal joint. Cytological examination revealed melanocytes with the presence of numerous blackish melanin pigments in the cytoplasm. Histopathological examination revealed that the tumor was comprised of heavily pigmented spindle shaped cells, arranged in sheets with a large nuclei and abundant granular black pigment in the cytoplasm. Following surgical removal of the mass, the animal recovered with no recurrence. Based on clinical examination, cytology and histopathological findings, the growth was diagnosed as cutaneous melanoma.

A three years old male pigeon weighing 400g (racing homer) was presented to Madras Veterinary College Teaching Hospital with the history of soft tissue growth on the keel region for the past six months and gradually increase in size was noticed. Physical examination revealed large tennis ball size soft tissue mass on the keel region. Cytological examination revealed the presence of inflammatory cells with serosanguineous background. Radiological examination revealed presence of soft tissue mass on the keel bone with no bony involvement. Surgical resection of tumour mass was performed under general anaesthesia. Histopathological examination confirmed liposarcoma in a pigeon. The bird recovered uneventfully on 10 th post-operative day without any complications.