In article results of studying of efficiency and quality of poultry-fanning production under influence chitosan are considered. It is established that the preparation promotes safety increase on 0,5%, efficiency on 6% and biological value of meat on 20% at chickens whom gave to drink chitosan in a dose of 5 mg/goal from 32 day age it) comparison with the control. Such technological reception leads to decrease the receipt in an organism of a chicken of microtoxins, heavy metals, products of a metabolism of bacteria

Data on studying of efficiency of application of immunobiological preparations on efficiency and other clinical and biochemical indicators for chickens-broilers are cited. It is established, that their application to chickens-broilers promotes increase of biological value of fowl as foodstuff and is economically expedient. Application of a preparation the Biococktail-NK in an optimum dose 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) has allowed to increase intensity of growth of chickens-broilers by 3,5%, to lower forage expenses for production of a gain of body weight of 1 kg on 4,95%, to raise safety of young growth of birds on 3,4 % and to lower a case of birds to 1,6% (technological norm of 5%). The carried out calculations have shown, that introduction of the Biococktail-NK in a ration of broilers is economically justified, as safety of young growth in 4th trial group has raised on 3,4%, in the third - on 2,5%, in the second - on 1,3%. On the basis of the spent research fowl of the delivered samples in which ration it was entered the probiotic Biococktail-NK from calculation 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) since daily age within the first 5 days into 4 cycles with an interval of 7 days till the end of the cultivation period is established, that on organoleptic, physical and chemical, bacteriological indicators, and also biological value and harmlessness does not concede to meat of control group and is good-quality. In the literature there are data about influence of biologically active substances on growth and development of bird. Despite it, about influence of probiotical and immunostimulatory preparations as separately, and in a complex with probiotics, on an organism of chickens-broilers it is not enough data that induces carrying out of scientific research in the given direction. Simultaneous use of probiotics on the basis of an intestinal stick in rations of chickens-broilers is the perspective directions. Proceeding from it, working out of new effective ways of increase of chickens-broilers efficiency with a view of reception of ecologically pure and safe products of poultry farming is actual for poultry-farming economy of Belarus.

Analysis of the optimal scheme of doses and rates of combined administration of probiotic Dialakt and immunostimulant Alveozan was realized in the conditions of the Republic of Belarus by the example of 1500 broiler chickens of cross Kobb- 500. Chickens of the first (controlled) group were given only total ration, balanced with the main nutrients. For the chickens of the second group were administrated with immunostimulant Alveozan with water starting from one day old age, every day in dose of 10 mkg/kg of body weight once a day in course of 5 days successively and with 7 days interval till the end of growing period; and probiotic Dialakt was administrated with water in dose of 0,1-0,2 ml/head (10,0-20,0 mln microbial bodies) starting from one day old age, once a day in course of 5 days successively and with 6 and 14 days intervals till the end of growing period. Chickens of the third group were administrated Alveozan in dose of 10 mkg/kg of body weight with drinking water once a day in course of 5 days with 10 days interval till the end of growing period; and Dialakt in dose of 0,1-0,2 ml/head with drinking water starting from one day old age, every day in course of 5 days with 6 and 14 days interval till the end of growing period. The research results showed the following optimal regime of complex application of the analyzed preparations: immunostimulant Dialakt - in dose of 0,1-0,2 ml/head with drinking water starting from one day old age, once a day in course of 3 days successively with 6 and 14 days intervals till the end of growing period; and immunostimulant Alveozan - in doze of 10 mkg/kg of body weight with drinking water once a day in course of 5 days with 10 days interval till the end of growing period. Complex application of Dialakt and Alveozan promoted the increasing of organometric indexes, specific volume and size of thymus in 1,5-1,8 times (P less than 0,01), Fabritsiya bursa - in 2 times (P less than 0,01) and lien - on 11,1% (P less than 0,05)

State of immune system of broiler chickens after administration into their diets of nonspecific immunostimulative drugs – bacterial liposaccharide Alveozan and spore-forming aerobic bacterium Bac. Alvei (KMIEhV-11) and probiotic on the basis of lactic acid bacillus Dialakt was studied in the conditions of the Republic of Belarus. In course of the study there was proved that the analyzed preparations had expressed immunogenic activity, rendered the positive influence on natural resistance of broiler chickens. Under action of preparations Alveozan and Dialakt in broiler chickens there were stated the following changes: improvement of protein absorption from gastro-intestinal tract in chickens at the age up to 19 days; there was achieved a hepatic protection effect at birds at the age up to 36 days. The specified changes did not depend on application regimen of the given preparations.

Studying of efficiency of application of a natural biological control agent BioLAD obtained as a result of cultivation of Fusarium sambucinum fungus in feeding of broiler chickens was realized in the conditions of the Republic of Belarus. There were studied 100 broiler chickens of Ross-308 cross. Broiler chickens of the first (control) group were fed with standard diet with PK-5-1. Broiler chickens of the experimental groups starting from one day old age till the end of the growing period (41 days old) were fed with feed supplement BioLAD in different doses: 0,25 ml/head (second group), 0,5 ml/head (third group), 1 ml/head (fourth group). Research results showed that natural biological control agent BioLAD in dose of 0,5 ml/head made it possible to increase chicken live weight on 11,2 %, viability - on 4,2%. Feeding charges per 1 kg of live weight gain were1,89 kg (second group), 1,81 kg (third group), 1,90 kg (fourth group). It made it possible to decrease the combined feed charges on 6,4% (second group), on 10,4% (third group), and on 5,9% (fourth group). Application of biological control agent BioLAD had an effect on poultry growth activity, promoted high level of chickens viability, increased the indices of general and local protection, stimulated metabolic processes

Influence of potassium orotate on hematological, immunomorphological indexes and and marrowy myelopoiesis of broiler chickens in the process of oral associated immunization against infectious bronchitis and poultry Newcastle disease was investigated in the conditions of the Republic of Belarus. There were studied 60 broiler chickens divided into 3 groups: one control group and two experimental ones. Research results established that potassium orotate application in combination with associated poultry immunization against infectious bronchitis and Newcastle disease increased the number of leucocytes and the volume of adenoid tissue as well as raised the lymphocytes density in thymus and bursa of Fabricius. In the bone marrow aspirates in 7 days after immunization in the control group there was stated the increasing of basophilic myelocytes number in comparison with the second experimental group. In 14 days in the control group there was noted the increasing of a total number of basophiles. In 21 days after immunization there were stated no considerable changes in the composition of basophil cells in the experimental groups. Research results showed that potassium orotate intensively stimulated the development of plasmocytic reaction in the conditions of multipartial immunization

Complex application Alveozan and Dialact conducts to the increase of perservance of birds on 2,1%, daily average additional weight on 3,6%, and also to the decrease in expenses of forages counting on 1 kg of a gain of live weight by 4,1%. Complex influence of Alveozan and Dialact stimulates growth and development lacto- and bifidoflora in a gastroenteric path, reduces quantity of aerobic microorganisms and oppresses a reproduction and settling of a gastroenteric path by bacteria intestinally-paratyphus groups. The economic efficiency of wording out 11,1 rubles on 1 ruble of additional expenses

Research of the influence of biologically active preparations of natural origin on zoological indices and quality of animal products was studied by the example of their application in broiler chicken diets in the conditions of the Republic of Belarus. On the basis of realized research it was established, that application of biologically active substances immunoamplifier Alveozan, probiotic Dialakt, probiotic Bifidoflorin liquid, prebiotic Biofon and prebiotic Biofon AIL (produced in the Republic of Belarus) did not render negative effect on quality of animal products (all studied meat samples had high quality). The received results testify to necessity of complex application of the above-stated preparations. Application of biologically active preparations made it possible to increase livability of growing birds on 100%, average live weight increase from 1,9 up to 5,1%, daily average weight gain - from 1,9 up to 5,1%, improvement of feed conversion ratio - from 18,3 up to 21%. All studied biologically active preparations made it possible to restore the physiological environment in poultry intestines, normal flora, to suppress the growth of pathogenic microorganisms. The above mentioned preparations could be applied both with preventive, and with the medical purposes

There was studied the influence of type Tf on indicators of iron transport fund of clinically healthy chickens-broilers of 46 day age; to establish a phenotype of chickens on transferrin type, the content of common iron in blood serum, common GILA, calculate indicators of the sated GILA and degrees of iron saturation. The received results lead to a conclusion: indicators of the content of common iron in serum at chickens with types Tf АВ, ВС and СD have doubtful distinctions, group of chickens with type Tf AC authentically (р0,05) is less on 1,36 mkmol/l or 8,05% in comparison with group of chickens containing type Tf AB. Values of the common GILA considerably differ at chickens-broilers between types Tf AB and Tf CD, AC and ВС. As common GILA is defined mainly by concentration of transferrin in blood serum, its values at chickens-broilers with different types can be regarded as different concentration transferrin in blood serum at these chickens. As transferrin possesses protective properties, it is possible to assume, that chickens with transferrin Tf CD type will possess the big immunity in comparison with chickens at which types Tf BC and Tf AB are established. At the same time slightly differing values of degree of iron saturation at chickens-broilers with different types of transferrin give the bases to consider, that different types of transferrin possess approximately identical GILA. | Целью работы явилось изучение влияния типа Tf на показатели транспортного фонда железа клинически здоровых цыплят - бройлеров 46 дневного возраста; установить фенотип цыплят по типу трансферрина, содержанию общего железа в сыворотке крови, общей железосвязывающей способности, рассчитать показатели насыщенной железосвязывающей способности и степени насыщения железа. Полученные результаты приводят к выводу: показатели содержания общего железа в сыворотке у цыплят с типами Tf АВ, ВС и СД имеют недостоверные различия, группа цыплят с типом Tf АС достоверно (р0,05) меньше на 1,36 мкмоль/л или 8,05% по сравнению с группой цыплят содержащих тип Tf АВ. Значения общей железосвязывающей способности значительно различаются у цыплят-бройлеров между типами Tf АВ и Tf CD, АС и ВС. Поскольку общая железосвязывающая способность определяется, главным образом, концентрацией трансферрина в сыворотке крови, то ее значения у цыплят-бройлеров с разными типами можно расценивать как разную концентрацию трансферрина в сыворотке крови у этих цыплят. Так как трансферрин обладает защитными свойствами, то можно предполагать, что цыплята с типом трансферрина Tf СД будут обладать большим иммунитетом по сравнению с цыплятами у которых установлены типы Tf ВС и Tf АВ. В то же время незначительно отличающиеся значения степени насыщения железа у цыплят-бройлеров с разными типами трансферрина дают основания считать, что разные типы трансферрина обладают примерно одинаковой железосвязывающей способностью.

In the conditions of the Republic of Belarus there was realized a morphological analysis of pectoral and leg muscles of broiler chickens of cross Cobb-500 in the process of administration of metabolic activator Catosal. Research results showed the positive influence of catosal on the myogenesis: diameter of muscle fiber, the amount of bigger diameter muscles fibers in the first order strand and homogeneity of muscle strands. Under the influence of Catosal preparation there was stated the increasing of the amount of muscle tissue in pectoral and leg parts of chicken carcass. | Приведены данные морфологических исследований грудных и ножных мышц цыплят-бройлеров кросса Кобб-500 при применении активатора метаболизма катозал. Установлено, что катозал активизирует миогенез за счет увеличения диаметра мышечных волокон, содержания в пучках первого порядка мышечных волокон большей толщины, а также большей однородности мышечных пусков. Под действием препарата происходит увеличение содержания мышечной ткани как в грудной части тушки, так и в окороках.