Morphological indexes in immune system organs of piglets which were vaccinated which were immunized by SPS vaccine (against salmonellosis (Salmonella), pasteurellosis (Pasteurella) and streptococcus) in combination with immunostimulative drugs and without them were studied in the conditions of the Republic of Belarus. Piglets of the first group were vaccinated against salmonellosis, pasteurellosis and streptoccocusis by SPS vaccine. Piglets of the second group were vaccinated by SPS vaccine in combination with vitamin C. Piglets of the third group were vaccinated by SPS vaccine with immunotstimulant sodium thiosulphate. The fourth (control) group of animals was administrated with normal saline. Animals were immunized twice, intramuscularly with 7 day interval and in dose 4 ml (primary), 5 ml (secondary). Vitamin С was added in dose 0,05g per head. Research results showed that immunization by SPS vaccine with sodium thiosulphate and Vitamin С activated the morphological reaction of immune system. Application of Vitamin С and sodium thiosulphate (30% concentration) in combination with SPS vaccine promoted the increasing of lymphoid nudels in lymphodnudus and lien, increasing of plasma cells quantity in 1,3-2,2 times, activation of micro- and macrophage reaction in 1,5-2,8 times in comparison with vaccinated animals

Experimental application of a vaccine against salmonellosis, pasteurellosis, and streptococcosis (SPS) for piglets of 30-35 days was realized in the conditions of the Republic of Belarus. Research results showed that administrationof sodium thyosulphate and vitamin С in combination with SPS vaccine promoted the statistically-valid increasing of preventive properties of blood serum of piglets and increasing of titers of specific antibodies to agents of pasteurellosis and a salmonellosis in 1,3-2 times, as well as increasing in blood serum of quantity of immunoglobulins and to reduction of quantity of globulins.

After the pathomorphological and histological studies of innards of fallen experimental animals in all realized experiments it was found that sheep and lambs infected with pneumoviral infections (Parainfluenza-3, Adenoviridae, respiratory streptococcosis infection) with their additional infestation with radioactive substances there was stated the acceleration of infectious process, and disease recrudesced up to 2-5 and more times (depending on irradiation doze). The immunity of sheep and lambs decreased caused by reproduction of viruses, and in acute cases animals died but in cases of mild forms the disease transformed into chronic form and caused animal death.

In the conditions of immunization of swine by experimental produced at Vitebsk Biofactory in the Republic of Belarus vaccines in blood of experimental swine there stated the morphological changes which pointed to formation of immune response.

Analysis of morphological characteristic and parameters of a thyroid gland of a thyroid gland of growing cattle stock made it possible to specificate the age-specific and species-specific parameters of adaptation of cattle in concrete conditions of environment was realized in the conditions of cattle breeding complexes of the Republic of Belarus. As a result of studies there were obtained new data on form-building processes, macromorphology, topography and referential parameters of thyroid gland of cattle breeds.

For the determination of efficiency of a new produced in the Republic of Belarus preparation Ehkvikar there was modeled a test with a diaphoresis of guinea pigs by means of their staying in a thermostat at a temperature of 45-50 deg C in course of 30 minutes. Before and after the test there was taken a blood test for its analysis. Results of the experiment showed that together with sudo the animals lost 1-2 % of their body. There was stated the increasing of all blood corpuscles as well as lowering in 1,3-1,47 times of such elements as chlorine, sodium, potassium, and also T lymphocytes and bursa-derived lymphocytes. Application Ehkvikar promoted the stabilization of biochemical and morphological parameters of blood, and also the immune status of laboratory animals. Thus, Ehkvikar preparation promoted the compensation of losses of electrolytes with sudor of guinea pigs and in future can be studied by an example of horses for completion of electrolytes losses in the conditions of increased physical exercises.

Results of chemical and toxicological estimation of an energized preparation, intended for increasing of performance ability and sports qualities of horses realized in the conditions of the Republic of Belarus were presented. The energized preparation included honey, lactalbumin hydrolyzate, pollen hydrolyzate, and teotropin. Chemical and toxicological estimation of the preparation included determination of physical, chemical and pharmacological compatibility of components of the preparation, acute and chronic toxicological characteristics, skin-resorbtive poison after single and long-term application at horse skin, topical-product-induced irritation and allergic action of the preparation. Research results showed that all components of the preparation were compatible among themselves. The preparation proved to be a low-hazardous substance (substance hazard category 4) and did not possess skin-absorptive, local-irritating and allergic action.

In the conditions of the Republic of Belarus there was made a hepatospecific metabolic profile of cattle blood serum for complex appraisal of liver functional condition. Age-specific peculiarities of biochemical indices including the composition of hepatospecific metabolic profile of cattle blood serum were revealed. On the basis of obtained results there were calculated the appropriate correction coefficients which must be taken into consideration in objective interpretation of laboratory research.

The analysis of swine farming production in CHUP Zopak-Agro has shown, that the decrease in the expense of forages and expenses on a payment on made production and increase of productive and breeding qualities of animals by purposeful selective-breeding work promote decrease in the cost price of a gain of live weight of pigs at the enterprise by 55,7 thousand rbl./с (or on 15,3%)

The recipe of mixed fodder is developed for cows with a 6-8 thousand kg yield of milk for a lactation during the period yield of milk, different the raised maintenance of a crude protein (18%) that allows to increase a yield of milk of animals by 6,6% (22,5 kg instead of 21,1 kg of 4% milk a day) to reduce the expense of forages on production unit to 6,4% (0,73 fodder units against 0,78 fodder units per 1 kg of milk). At the expense of additional production economic benefit makes 104,4 thousand rbl. counting on 1 head