Milk is an important food substance and has a complex polydisperse system. The main components of milk consist of lactose, protein, and lipids. Mineral substances and vitamins are also present in milk as minor nutrients. Lactose known as milk sugar is the only carbohydrate in milk and it consists of glucose and galactose. The content of lactose in milk has varied according to milk types. Moreover, it is the most important energy source during the first years of human life, providing almost half of the total energy needed by newborns. Lactose is obtained industrially from the residues of cheese and casein production processes. Lactulose, lactitol, lactobionic acid, galactooligosaccharide, lactosucrose, epilactose, and tagatose are commonly known lactose derivatives. These derivates are produced from lactose using various methods such as epimerization, oxidation, and reduction. In this review, up-to-date information about lactose, lactose derivatives, and the production methods of lactose derivatives are given.

This study aimed to investigate the presence of Aflatoxin M1 (AFM1) in raw buffalo milk and buffalo milk products such as cheese, yogurt, cream, and ice cream by ELISA technique. In the study, 175 samples were investigated, and it was determined that 146 (83.43%) of the samples had AFM1 concentrations below the LOD (limit of detection) value. In 29 samples (16.57%), the AFM1 concentration exceeded the LOD value, and in 7 (4%) of these, the AFM1 concentration was above the legal limits (50 ng/L). While AFM1 was not detected in raw buffalo milk samples, the presence of AFM1 in cheese, yogurt, cream, and ice cream samples was found to be 2.85%, 2.85%, 62.85%, and 14.3%, respectively. 2.85% of cheese samples and 17.1% of cream samples were found contaminated with AFM1 above the allowed legal limits (50 ng/L). As a result, it was determined that the potential for exposure to AFM1 by consuming buffalo cream was higher than the consumption of buffalo milk and other buffalo milk products. However, the detection of AFM1 above legal limits in buffalo milk products poses a serious risk to public health. Therefore, it is extremely necessary for public health to develop effective monitoring programs to control aflatoxin contamination in milk and new strategies to maintain inspections.

Globally, 16.9% of milk used by humans is taken from different species other than a cow. These species are sheep, horse, yak, ass, goat, camel and buffalo. The global camel (Camelus dromedarius) population is about 34 million head with sharing of almost 0.4% of world’s non-cattle milk. Within the last 20 years, the curiosity of camel farming is amassed remarkably in different countries of the world including the Netherland, Italy and USA for camel milk production. The camel is considered as a goal animal of the 21st century because it produces high quality milk under extreme temperature, deficiency of pasture and dearth of water. The average milk production of camel fluctuates from 4 to 30 lt with lactation length ranges from 9 to18 months having peak yield in second to the third month of lactation. Camel’s milk is used globally because of its salty taste, high vitamin C concentration and its medicinal properties. Nevertheless, it gives many valuable benefits such as treatment of autism, control diabetes and allergy, prevention from liver cirrhosis and replacer of cow milk to avoid an infant’s allergic reaction. The camel milk is a natural treatment of diabetes as it has a substantial result in a decrease of mean blood glucose and conserves necessary insulin doses. Camel milk constitutes of protein (2.5-4.5%), fat (2.9-5.5%), solid not fat (8.9 -14.3%), ash (0.35-0.95%), lactose (2.9-5.8%) and water (86.3-88.5%) as mean specific gravity is 1.03. Due to its distinct properties, the consumption of camel milk is increasing day by day and a number of industries are working to promote camel milk production and processing. Therefore, the tenacity of this review article is to explicate the beneficial uses and production of camel milk over the globe.

This study investigated the prevalence and concentration of antibiotic residues in twenty brands of milk. Determination and quantification of antibiotic residues was done using High Performance Liquid Chromatography. Aerobic plate count was carried out and the associated bacteria isolated. Identification of bacteria was done using standard microbiological methods. Molecular characterization and identification of bacterial isolates was done using 16S rRNA gene sequencing method. Antibiotic sensitivity was carried out on bacterial isolates using disc diffusion method. Plasmid profile of drug resistant isolates was done using alkaline analysis method. Comparison of means was done using Analysis of Variance. Antibiotic residues were detected in 10 (50%) of the 20 milk brands analyzed. The residual levels of tetracycline, oxytetracycline and chlortetracycline ranged between 5ng/kg and 1569ng/kg while none of the samples had doxycycline residues. The prevalence of tetracycline residues in evaporated milk brands and powdered milk samples were 100 and 23 % respectively. The aerobic plate counts ranged from 2.5 × 102 to 6.5 × 102 CFU∕mL for evaporated milk and 2.5 × 101 to 6.0 × 101 CFU∕mL for powdered milk. A total of ten bacterial species were isolated and identified. Susceptibility result showed that 95% of the isolates were sensitive to erythromycin, cefuroxime and gentamycin; 12.5% were resistant to tetracycline and ampicillin, 10% were resistant to ofloxacin and 7.5% to doxycycline and penicillin. Five of the bacterial isolates were resistant to more than one class of antibiotics. Resistant isolates subjected to plasmid profiling had detectable plasmids with estimated sizes between 120bp and 1000bp. The obtained results provide evidence that the presence of antibiotic residues in evaporated and powdered milk is an indication that the public is exposed to the harmful effects of the residues.

The aim of this study was to explore the concentrations of PAEs (Phthalate esters) in milk in Türkiye. For this purpose, a methodology was developed to quantify eight different PAEs in milk samples using a combination of dispersive solid-phase extraction (dSPE) and Liquid Chromatography coupled with Tandem Mass Spectrometry (LC-MS/MS). Employing this methodology, the concentrations of PAEs were evaluated in 34 milk samples. Results indicated the presence of PAEs in the milk samples; however, all tested compounds remained within the specific migration limits established by the EU. Among the analyzed PAEs, BBP (Benzyl butyl phthalate) was not detected in any samples, while DMP (di-methyl phthalate) (ND-5.51 µg/L) and DBP (di-butyl phthalate) (ND-7.91 µg/L) exhibited the lowest concentrations. DEHP (bis(2-ethylhexyl)) was identified as the most prevalent plasticizer with a maximum concentration of 41.31 µg/L. In conclusion, this study successfully investigated PAE concentrations in Turkish milk samples using a developed methodology. The results indicated the presence of PAEs within EU-established limits, with DEHP being the predominant plasticizer. Further research and monitoring efforts are crucial to ensure ongoing safety in packaged milk products.

This study aimed to investigate the presence of Aflatoxin M1 (AFM1) in raw buffalo milk and buffalo milk products such as cheese, yogurt, cream, and ice cream by ELISA technique. In the study, 175 samples were investigated, and it was determined that 146 (83.43%) of the samples had AFM1 concentrations below the LOD (limit of detection) value. In 29 samples (16.57%), the AFM1 concentration exceeded the LOD value, and in 7 (4%) of these, the AFM1 concentration was above the legal limits (50 ng/L). While AFM1 was not detected in raw buffalo milk samples, the presence of AFM1 in cheese, yogurt, cream, and ice cream samples was found to be 2.85%, 2.85%, 62.85%, and 14.3%, respectively. 2.85% of cheese samples and 17.1% of cream samples were found contaminated with AFM1 above the allowed legal limits (50 ng/L). As a result, it was determined that the potential for exposure to AFM1 by consuming buffalo cream was higher than the consumption of buffalo milk and other buffalo milk products. However, the detection of AFM1 above legal limits in buffalo milk products poses a serious risk to public health. Therefore, it is extremely necessary for public health to develop effective monitoring programs to control aflatoxin contamination in milk and new strategies to maintain inspections.

The aim of the study was to describe the scenario of the present condition of production and management system of dairy buffalo at Haor areas of Sylhet in Bangladesh. Data were collected between February 2019 and January 2020. Sixty dairy farmers and thirty indigenous dairy buffaloes were selected for the study purpose. All respondent farmers were male and 65% were in between 40 to 50 years of age. Parity number had a significant relation in response of body weight. Quality analysis of milk showed that buffaloes which were reared at Haor areas have more fat content on an average 7.88% than buffaloes which were reared conventional dairy farm containing 7.34%. Price of buffalo’s milk and meat were varied with the seasonal changes, lower in winter season. All farmers fed the buffaloes only with green grass in winter. Four major diseases of buffaloes were found in Haor areas where the percentage of foot and mouth diseases was 15.59% followed by black quarter (11.01%), anthrax (7.34%) and hemorrhagic septicemia (6.42%). The buffaloes were not dewormed so parasitic infestations dramatically increased and easily transferred from one to another. The farmers had not enough knowledge about regular vaccination. But in contrast with profitability, total benefit cost ratio from buffalo rearing was 1:1.56 annually.

Globally, 16.9% of milk used by humans is taken from different species other than a cow. These species are sheep, horse, yak, ass, goat, camel and buffalo. The global camel (Camelus dromedarius) population is about 34 million head with sharing of almost 0.4% of world’s non-cattle milk. Within the last 20 years, the curiosity of camel farming is amassed remarkably in different countries of the world including the Netherland, Italy and USA for camel milk production. The camel is considered as a goal animal of the 21st century because it produces high quality milk under extreme temperature, deficiency of pasture and dearth of water. The average milk production of camel fluctuates from 4 to 30 lt with lactation length ranges from 9 to18 months having peak yield in second to the third month of lactation. Camel’s milk is used globally because of its salty taste, high vitamin C concentration and its medicinal properties. Nevertheless, it gives many valuable benefits such as treatment of autism, control diabetes and allergy, prevention from liver cirrhosis and replacer of cow milk to avoid an infant’s allergic reaction. The camel milk is a natural treatment of diabetes as it has a substantial result in a decrease of mean blood glucose and conserves necessary insulin doses. Camel milk constitutes of protein (2.5-4.5%), fat (2.9-5.5%), solid not fat (8.9 -14.3%), ash (0.35-0.95%), lactose (2.9-5.8%) and water (86.3-88.5%) as mean specific gravity is 1.03. Due to its distinct properties, the consumption of camel milk is increasing day by day and a number of industries are working to promote camel milk production and processing. Therefore, the tenacity of this review article is to explicate the beneficial uses and production of camel milk over the globe.

One-year investigation is carried out aimed at evaluating all incomes and costs with a specific focus on the impact of feeding factors in 12 Holstein dairy farms (in total 284 cows) in Kosovo. The cost of on-farm produced feeds; the price of purchased feeds and the price of milk were used for the analysis. All costs created during this period are duly registered and considered in the analysis. Economic analysis showed that prices of on-farm produced feed were much lower (30 €/ton for silages and for hay). Average daily feed cost was 2.33 €/cow/day, while milk income was only 4.9 €/d. Individual feed groups contributed to total milk cost as follows: silages with 0.04 €/kg, dry roughages with 0.02 €/kg, and concentrates with 0.10 €/kg, while all other factors taken 0.13 €/kg of milk price. This study showed that feed was the largest farm expense making 68% of total farm costs.

Milk traits of sheep are affected by many environmental and genetic factors. These traits are quantitative traits and are determined by many genes. This study aimed to investigate polymorphisms of milk-related Fatty-acid synthase (FASN), Stearoyl-CoA desaturase (SCD1), and solute carrier 27A3 (SLC27A3) genes in cross-bred Hamdani sheep. Blood samples were collected from 100 healthy cross-bred Hamdani ewes from the jugular vein into K3-EDTA-containing tubes. Genomic DNA was extracted using a commercial DNA isolation kit. PCR products of FASN (275 bp), SCD1 (225 bp), SLC27A3-P1 (341 bp), and SLC27A3-P2 (319 bp) were subjected to restriction fragment length polymorphism (RFLP) analysis using SSil (AciI), Cfr13I, AluI, and Hpy188III the restriction enzyme, respectively. However, all gene regions were found to be monomorphic. In the study, only TT, AA, AA, and GG genotypes were detected for FASN, SCD1, SLC27A3-P1, and SLC27A3-P2, respectively. Allele and genotype frequencies were 1.00 for all genotypes and alleles. Although this study did not reveal favorable genotypes in FASN, SCD1, and SLC27A3 genes that can be used for milk traits, more comprehensive studies with larger sample sizes should be conducted to investigate polymorphisms in cross-bred Hamdani sheep.