Mathematical modelling and simulation of fermentation process for citric acid production
1993
Zlateva, P. | Simeonov, L. (Central Laboratory of Bioinstrumentation and Automation - BAN, Sofia (Bulgaria)) | Kajmakchiev, A.
The modelling of citric acid production in batch culture was on the basis of experimental studies. The unknown kinetics coefficients were estimated by least squares identification technique minimizing a quadratic performance index by the method of Hooke and Jeeves. The influence of the integration method and the time for one simulation was investigated.
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