Results of acute sistemic and local toxicity investigation of medical disinfectant Lotagen

Djermanovic, Dj.; Vujovic, V.; Djalovic, A.; Banicevic, G.; Novakovic, Z.

Results of acute sistemic and local toxicity investigation of medical disinfectant Lotagen

1997

Djermanovic, Dj. (Veterinarski zavod, Zemun (Yugoslavia)) | Vujovic, V. | Djalovic, A. | Banicevic, G. | Novakovic, Z.

Numerous cases of adverse effects of dermatological drugs and other substances for topical application have suggested the importance of evaluation of their possible systemic toxicity, dermal toxicity and local irritative effect. In studies of systemic and local toxicity of Lotagen, medical disinfectant, we determined that a single oral LD50 dose of Lotagen was 2,187.5 mg/kg BW. Studies of local cutaneous toxicity have shown that not a single studied form of Lotagen induces any local reaction on the rabbit skin. Study of irritative effect on the rabbit eye have shown that 36 and 20 Lotagen solutions induce florid irreversible reaction, while the application of 4 Lotagen solution into the rabbit eye does not provoke any local reaction.

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Mots clés AGROVOC

application rates conejo (oryctolagus) desinfectantes disinfectants dose d'application lapin (oryctolagus) mice rabbits skin tests souris toxicidad toxicity

Informations bibliographiques

Editeur

Jugoslovensko udruzenje strucnjaka iz oblasti proizvodnje, ispitivanja, kontrole i prometa lekova za upotrebu u veterini

Pagination

p. 207-209

D'autres materias

Pruebas cutaneas; Desinfectant; Test cutane; Raton; Toxicite; Dosis de aplicacion

Langue

serbe

Note

Summary (En)

3 tables; 6 ref. Text in cyrillic.

Titre traduit

Rezultati ispitivanja akutne sistemske i lokalne toksicnosti medicinskog dezinficijensa Lotagena

Type

Summary; Conference

Source

Proceedings of the 3rd conference on drugs for veterinary use, Igalo [Yugoslavia], April 14-18, 1997, Zivanov, D. (ed.).- Beograd (Yugoslavia): Jugoslovensko udruzenje strucnjaka iz oblasti proizvodnje, ispitivanja, kontrole i prometa lekova za upotrebu u veterini, 1997

Conférence

3. savetovanje o lekovima za upotrebu u veterini, Igalo (Yugoslavia), 14-18 Apr 1997

Sur AGRIS depuis: 1998-08-15

Format: AGRIS AP

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