A new abietane diterpene and anti-complementary constituents from Juniperus tibetica
2021
Zeng, Dong-Lin | Wang, Chang-Yue | Gao, Hui-Qin | Chen, Dao-Feng | Lu, Yan
Anti-complementary activity-guided fractionation led to the isolation of a new abietane diterpene (1) and twenty-five known compounds (2–26) from the twigs and leaves of Juniperus tibetica. All the compounds were isolated from J. tibetica for the first time. The structure of 1 was assigned by spectroscopic data and X-ray crystallography analysis. Five lignans (2, 3, 7, 9 and 10), two flavones (19 and 22), and one coumarin (23) exhibited anti-complementary activity with CH₅₀ values ranging from 0.3 to 3.69 mM.
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