A new abietane diterpene and anti-complementary constituents from Juniperus tibetica
2021
Zeng, Dong-Lin | Wang, Chang-Yue | Gao, Hui-Qin | Chen, Dao-Feng | Lu, Yan
Anti-complementary activity-guided fractionation led to the isolation of a new abietane diterpene (1) and twenty-five known compounds (2–26) from the twigs and leaves of Juniperus tibetica. All the compounds were isolated from J. tibetica for the first time. The structure of 1 was assigned by spectroscopic data and X-ray crystallography analysis. Five lignans (2, 3, 7, 9 and 10), two flavones (19 and 22), and one coumarin (23) exhibited anti-complementary activity with CH₅₀ values ranging from 0.3 to 3.69 mM.
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书目信息
Natural product research
卷
35
期
20
页码
3452
- 3459
ISSN
1478-6427
出版者
Taylor & Francis
其它主题
Abietane diterpene; Anti-complementary activity; X-ray diffraction; Coumarin; Juniperus tibetica
语言
英语
注释
This research was supported by the National Natural Science Foundation of China [grant number 81673690]; the Ministry of Science and Technology of China [grant number 2019YFC1711006]; the major project of Science and Technology of Tibet autonomous region, China [grant numer XZ201801-GH-13]; and the Development Project of Shanghai Peak Disciplines-Integrative Medicine [grant number 20180101].
类型
Journal Article; Text
2024-02-27
MODS