Influence of lipid composition on pediocin PA-1 binding to phospholipid vesicles
1998
Chen, Y. | Ludescher, R.D. | Montville, T.J.
Pediocin PA-1 bound to anionic lipid vesicles with saturated or unsaturated fatty acid chains in a lipid concentration-dependent fashion. Little change in binding parameters was observed for zwitterionic lipid vesicles. Decreasing the anionic lipid content of the vesicles gave a higher relative dissociation constant for the peptide-lipid interactions and further supports the electrostatic interaction model of binding.
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