Anti-inflammatory constituents from Phyllostachys makinoi Hayata

Liaw, Chia-Ching; Lin, Yu-Chi; Wu, Shao-Yu; Kuo, Jenny Chun-Ling; Lin, Zhi-Hu; Lin, Kai-Wei; Hui-Chi, Huang; Yang Kuo, Li-Ming; Kuo, Yao-Haur

Anti-inflammatory constituents from Phyllostachys makinoi Hayata

2022

A novel chromone analogue, phyllomakin A (1), and a new flavonolignan, (-)-quiquelignan C (2), along with 18 phenolic and 2 triterpenoids, were isolated from the leaves of Phyllostachys makinoi Hayata. The structures of 1–22 were elucidated by an application of various spectroscopic analyses (1D & 2D NMR and MS) and compared with reported data. A biological evaluation showed that compound 3 had very potent anti-NO production activity (IC₅₀ = 4.80 µM), while compounds 2, 6, 11, and 15 showed moderate inhibitory effects (IC₅₀ = 10.19, 13.26, 13.56, and 10.96 µM, respectively) without affecting cell viability at 20 μM.

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Mots clés AGROVOC

phyllostachys research triterpenoids

Informations bibliographiques

Publié dans

Natural product research

Volume 36 Numéro 6 Pagination 1425 - 1432 ISSN 1478-6427

Editeur

American Chemical Society

D'autres materias

Phyllostachys makinoi; Anti-no production; Biological assessment; Phyllomakin a; Cell viability; Quiquelignan c

Langue

anglais

Note

This work was supported by the Ministry of Health and Welfare Taiwan under Grants MM10701-0117 and MOHW108-NRICM-B-315-144002; the Ministry of Sciences and Technology under Grant MOST 105-2320-B-077-001-MY2 in Taiwan.

Type

Journal Article; Text

Sur AGRIS depuis: 2024-02-28

Format: MODS

Fournisseur de données

Cette notice bibliographique a été fournie par National Agricultural Library

Découvrez la collection de ce fournisseur de données dans AGRIS

Liens

DOI https://dx.doi.org/10.1080/14786419.2021.1885406

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