Platform technologies for modern vaccine manufacturing

Charlton Hume, Hayley K.; Lua, Linda H.L.

Platform technologies for modern vaccine manufacturing

2017

Charlton Hume, Hayley K. | Lua, Linda H.L.

Improved understanding of antigenic components and their interaction with the immune system, as supported by computational tools, permits a sophisticated approach to modern vaccine design. Vaccine platforms provide an effective tool by which strategically designed peptide and protein antigens are modularized to enhance their immunogenicity. These modular vaccine platforms can overcome issues faced by traditional vaccine manufacturing and have the potential to generate safe vaccines, rapidly and at a low cost. This review introduces two promising platforms based on virus-like particle and liposome, and discusses the methodologies and challenges.

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Mots clés AGROVOC

antigens immune response immune system manufacturing vaccines

Informations bibliographiques

Publié dans

Vaccine

Volume 35 Numéro 35 Pagination 4480 - 4485 ISSN 0264-410X

Editeur

Elsevier Ltd

D'autres materias

Vaccine design; Platform technology; Virus-like particle; Liposome; Modular

Langue

anglais

Licence

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Type

Journal Article; Text

Sur AGRIS depuis: 2024-02-28

Format: MODS

Fournisseur de données

Cette notice bibliographique a été fournie par National Agricultural Library

Découvrez la collection de ce fournisseur de données dans AGRIS

Liens

DOI DOI https://dx.doi.org/10.1016/j.vaccine.2017.02.069

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