Platform technologies for modern vaccine manufacturing

Charlton Hume, Hayley K.; Lua, Linda H.L.

Platform technologies for modern vaccine manufacturing

2017

Charlton Hume, Hayley K. | Lua, Linda H.L.

Improved understanding of antigenic components and their interaction with the immune system, as supported by computational tools, permits a sophisticated approach to modern vaccine design. Vaccine platforms provide an effective tool by which strategically designed peptide and protein antigens are modularized to enhance their immunogenicity. These modular vaccine platforms can overcome issues faced by traditional vaccine manufacturing and have the potential to generate safe vaccines, rapidly and at a low cost. This review introduces two promising platforms based on virus-like particle and liposome, and discusses the methodologies and challenges.

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Ключевые слова АГРОВОК

antigens immune response immune system manufacturing vaccines

Библиографическая информация

Опубликовано в

Vaccine

Том 35 Выпуск 35 Нумерация страниц 4480 - 4485 ISSN 0264-410X

Издатель

Elsevier Ltd

Другие темы

Vaccine design; Platform technology; Virus-like particle; Liposome; Modular

Язык

Английский

Лицензия

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Тип

Journal Article; Text

В АГРИСе с: 2024-02-28

Формат: MODS

Поставщик данных

Эту запись предоставил National Agricultural Library

Откройте коллекцию этого поставщика данных в AGRIS

Ссылки

DOI DOI https://dx.doi.org/10.1016/j.vaccine.2017.02.069

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