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Investigation on the efficacy of a utility model „Remote piston injector for veterinary use“ Texte intégral
2022
R. Mihaylov | D. Kanakov | S. Krastev | Z. Zheleva
Abstract. The effectiveness of a utility model – remote piston injector for veterinary use was investigated. The injector is from the field of applied veterinary technology, hand tools, instruments and accessories for the application of treatment and prevention of domestic and wild animals. It can be used safely for the application of various types of veterinary medicinal products in relation to animal health and welfare. The utility model is part of the technique that serves to improve veterinary care and is a mobile tool related to the prevention, diagnosis and treatment of animal diseases. It has been found that it successfully provides treatment to dangerous animals with drugs, vaccines, etc. from a distance safely for humans, using cheap disposable or remote syringes that are protected by the injector housing.
Afficher plus [+] Moins [-]Efficacy of herbicides, herbicide combinations and herbicide tank mixtures on lentil (Lens culinaris Medik.) Texte intégral
2022
G. Delchev
Abstract. The research was conducted during 2019 – 2022 on pellic vertisol soil type. Under investigation was lentil cultivar Ilina (Lens culinaris Medik.). A total of 23 variants were investigated: untreated control, 8 herbicides – Pendistar 40 SC (pendimethalin), Dual gold 960 EC (S-metolachlor), Lentagran VP (pyridate), Challenge 600 SC (aclonifen), Zencor 600 SC (metribuzin), Wish top (quizalofop-P-ethyl), Zetrola (propaquizafop) and Passat 40 (imazamox), as well as combinations and tank mixtures between them. Soil-applied herbicides were used during the period after sowing before emergence. Foliar-applied herbicides were used during 2-3, 4-5 or 6-7 real leaf stage of the lentil. All of the herbicides, herbicide combinations and herbicide tank-mixtures were applied in a working solution of 300 l/ha. Mixing of foliar-applied herbicides was done in the tank on the sprayer. The combinations of herbicide Lentagran with soil-applied herbicides Pendistar and Dual gold, as well as herbicides Challenge with foliar-applied herbicides Wish top and Zetrola had an additive effect on herbicide efficacy. The herbicides Lentagran and Zencor, as well as their combinations, successfully controlled Clearfield and ExpressSun sunflower self-sown plants in lentil crops. The foliar-applied herbicide Passat controlled all annual and perennial broadleaved and graminaceous weeds and self-sown plants. The use of foliar-applied herbicide Passat and soil-applied herbicide Zencor at a dose of 900 g/ha led to high phytotoxicity in lentil plants – rate 3 according to the scale of EWRS. Double use of Zencor at doses of 600 + 300 g/ha and the combined use of the herbicides Challenge and Zetrola led to low phytotoxicity in lentil – rate 2 according to the scale of EWRS. The highest yields of lentil seeds were obtained by use of herbicide combinations Pendistar 5 l/ha + Lentagran 500 + 500 ml/ha and Pendistar 5 l/ha + Lentagran 1 l/ha. High yields were also obtained when combining Challenge 3 + 1 l/ha with Wish top 1.25 l/ha, as well as by the herbicide combination Challenge 4 l/ha + Wish top 1.25 l/ha.
Afficher plus [+] Moins [-]A Review on the Potential Species of the Zingiberaceae Family with Anti-viral Efficacy Towards Enveloped Viruses Texte intégral
2022
APB Balaji | Srinivasan Bhuvaneswari | Leon Stephan Raj | Giridharan Bupesh | Kishore Kumar Meenakshisundaram | Konda Mani Saravanan
Natural products are a great wellspring of biodiversity for finding novel antivirals, exposing new interactions between structure and operation and creating successful defensive or remedial methodologies against viral diseases. The members of Zingiberaceae traditional plant and herbal products have robust anti-viral action, and their findings will further lead to the production of derivatives and therapeutic. Additionally, it highlights the insight of utilizing these phytoextracts or their constituent compounds as an emergency prophylactic medicine during the pandemic or endemic situations for novel viruses. In this connection, this review investigates the potential candidates of the Zingiberaceae family, consisting of bioactive phytocompounds with proven antiviral efficacy against enveloped viruses. The present study was based on published antiviral efficacy of Curcuma longa, Zingiber officinale, Kaempferia parviflora, Aframomum melegueta Elettaria cardamomum, Alpina Sps (belongs to the Zingiberaceae family) towards the enveloped viruses. The relevant data was searched in Scopus”, “Scifinder”, “Springer”, “Pubmed”, “Google scholar” “Wiley”, “Web of Science”, “Cochrane “Library”, “Embase”, Dissertations, theses, books, and technical reports. Meticulously articles were screened with the subject relevancy and categorized for their ethnopharmacological significance with in-depth analysis. We have comprehensively elucidated the antiviral potency of phytoextracts, major composition, key compounds, mode of action, molecular evidence, immunological relevance, and potential bioactive phytocompounds of these five species belonging to the Zingiberaceae family. Conveniently, these phytoextracts exhibited multimode activity in combating the dreadful enveloped viruses.
Afficher plus [+] Moins [-]Promoting Tunisian agri-food start-up. A study on the self-efficacy of aspiring entrepreneurs Texte intégral
2022
Filippo Fiume | Fagioli Elena Viganò
In 2011, Tunisia went through a revolution which transformed its modern history. Currently, the country is experiencing a moment of transition in which it faces problems, both on a social and economic level. The region Kroumerie-Mogods, in the northwest, includes the three Governorates of Jendouba, Beja and Bizerte, is strongly affected by past economic policies. Despite having great potential in terms of both natural resources and economic opportunities, the local population appears to be among the poorest in the country, suffering from high level of unemployment, widespread poverty and substantial inequalities. In this context, a Development Cooperation project was implemented with the aim of creating new employment opportunities, especially for young people and women, through the enhancement of the territory and its agricultural products with the support of new entrepreneurial initiatives. Principal Component Analysis and Logit model were used to analyse the Self-Efficacy (SE) of young aspiring entrepreneurs and to evaluate its effects on the promotion of personal entrepreneurial projects. The study shows that past involvement in business key activities, as commercial experiences, social commitments and sustainable waste management, represent a decisive element for the promotion of personal business projects in agri-food sector.
Afficher plus [+] Moins [-]The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats Texte intégral
2022
Wissam Abdullah Alhayani
Cutaneous wound healing processes start at the beginning of the trauma leading to impairment of physical and functional tissue continuity. The present work aimed to clarify the efficacy of stem cells loaded in acacia gum hydrogel and acacia gum hydrogel on skin wound healing in rats. Thirty-six adult male rats (Wister rats). The weight of the rats was estimated between 150-160 grams and the animals were divided into three groups (n=12). In Group A (control group), the surgical skin wound was established and treated with normal saline only. Group B: surgical skin wound was made and covered with Acacia gum hydrogel. Group C: surgical skin wound was made and covered with mesenchymal stem cells loaded in Acacia gum hydrogel. Examination of wound healing on days 3, 7, 14 and 21 for gross and microscopic pathological changes. The gross pathological evaluation showed no significant difference between all groups but the histopathological result showed the Acacia gum improved wound recovery better than the control group, although the wound was not completely closed on day 21 in Acacia gum and control groups contrary to the stem cells treated group, which showed complete wound closure. The best ever histopathological result of wounds healing in mesenchymal stem cells loaded in acacia gum hydrogel treated groups.
Afficher plus [+] Moins [-]Effect of sainfoin ( Onobrychis viciifolia ) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses Texte intégral
2022
Malsa, Joshua | Courtot, Elise | Boisseau, Michel | Dumont, Bertrand | Gombault, Pascale | Kuzmina, Tetiana, A. | Basiaga, Marta | Lluch, Jérôme | Annonay, Gwenolah | Dhorne-Pollet, Sophie | Mach, Núria | Sutra, Jean-François | Wimel, Laurence | Dubois, Cédric | Guégnard, Fabrice | Serreau, Delphine | Lespine, Anne | Sallé, Guillaume | Fleurance, Géraldine | Infectiologie et Santé Publique (ISP) ; Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Unité Mixte de Recherche sur les Herbivores - UMR 1213 (UMRH) ; VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Multifolia | I.I. Schmalhausen Institute of Zoology of NASU ; National Academy of Sciences of Ukraine = Національна академія наук України = Académie nationale des sciences d'Ukraine (NASU / НАН України) | University of Agriculture in Krakow | Génome et Transcriptome - Plateforme Génomique (GeT-PlaGe) ; Plateforme Génome & Transcriptome (GET) ; Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL) ; Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL) ; Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Génétique Animale et Biologie Intégrative (GABI) ; AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Interactions hôtes-agents pathogènes [Toulouse] (IHAP) ; Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Innovations Thérapeutiques et Résistances (InTheRes) ; Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Institut Français du Cheval et de l'Equitation [Saumur] (IFCE) | This work benefited from the financial support of the Institut Français du Cheval et de l’Équitation (IFCE) and Institut Carnot France Future Élevage (F2E). Joshua Malsa is a grateful recipient of a joint Fond Eperon and IFCE fellowship.We are grateful to the GenoToul bioinformatics platform (https://doi.org/10.15454/1.5572369328961167E12) for providing computing and storage resources.
The raw data files and associated R scripts are available under the following repository: https://github.com/Joshua-Malsa/Sainfoin-paper.git. | International audience | Alternative strategies to chemical anthelmintics are needed for the sustainable control of equine strongylids. Bioactive forages like sainfoin ( Onobrychis viciifolia ) could contribute to reducing drug use, with the first hints of in vitro activity against cyathostomin free-living stages observed in the past. We analysed the effect of a sainfoin-rich diet on cyathostomin population and the efficacy of oral ivermectin treatment. Two groups of 10 naturally infected horses were enrolled in a 78-day experimental trial. Following a 1-week adaptation period, they were either fed with dehydrated sainfoin pellets (70% of their diet dry matter) or with alfalfa pellets (control group) for 21-days. No difference was found between the average fecal egg counts (FECs) of the two groups, but a significantly lower increase in larval development rate was observed for the sainfoin group, at the end of the trial. Quantification of cyathostomin species abundances with an ITS-2-based metabarcoding approach revealed that the sainfoin diet did not affect the nemabiome structure compared to the control diet. Following oral ivermectin treatment of all horses on day 21, the drug concentration was lower in horses fed with sainfoin, and cyathostomin eggs reappeared earlier in that group. Our results demonstrated that short-term consumption of a sainfoin-rich diet does not decrease cyathostomin FEC but seems to slightly reduce larval development. Consumption of dehydrated sainfoin pellets also negatively affected ivermectin pharmacokinetics, underscoring the need to monitor horse feeding regimes when assessing ivermectin efficacy in the field.
Afficher plus [+] Moins [-]Evaluation of the efficacy of Flupyradifurone against Bemisia tabaci on cassava in Tanzania Texte intégral
2022
Issa, K.A. | Wosula, E.N. | Stephano, F. | Legg, James P.
A novel butenolide insecticide—flupyradifurone (Sivanto SL 200)—was evaluated for efficacy against cassava-colonizing Bemisia tabaci whitefly under laboratory, screenhouse and field conditions. LC50 values from leaf disc spray assays were comparable for both flupyradifurone (12.7 g a.i/100 L) and imidacloprid (12.6 g a.i/100 L). Both insecticides caused high levels of adult whitefly mortality in leaf disc and leaf dip assays when compared to untreated controls. In screenhouse-based trials, longer soaking (60 min) with flupyradifurone or imidacloprid was more effective than shorter soaking durations (15 or 30 min). In field spraying experiments, flupyradifurone significantly reduced whiteflies, and both insecticides demonstrated powerful knockdown effects on whitefly adult abundances over a period up to 24 h. Single cutting dip application of flupyradifurone reduced whitefly adult abundance by 2 to 6 times, and nymphs by 2 to 13 times. Lower whitefly abundances resulting from insecticide application reduced the incidence of CMD or CBSD. In addition, in field experiments, whiteflies were fewer during the long rainy season (Masika) and on cassava variety Mkuranga1. The findings from this study demonstrate that cutting dips with flupyradifurone could be incorporated as a management tactic against cassava whiteflies. This would ideally be combined in an IPM strategy with other cassava virus and virus vector management tactics including host-plant resistance, phytosanitation and the use of clean seed.
Afficher plus [+] Moins [-]DEPENDENCE OF ANTHELMINTIC EFFICACY ON PLANT COMPOSITION Texte intégral
2022
Saleh Maharramov
In our studies, the method of helminthological autopsy was used to determine the anthelmintic efficacy of garlic, wormwood, licorice, harmala, camel thorn and ephedra. We conducted experiments on 42 sheep, collected in 7 groups, consisting of 6 experimental, 1 control group. We divided the animals into groups depending on the degree of infection with helminths, on weight and age. Therefore, after determining the infection with helminths of the studied animals by helminthoscopic methods, we divided them into groups. For 2 days, each group I sheep naturally infected with gastrointestinal nematodes was given 150 g of garlic juice mixed with water. Animals of group II were fed 150 g of wormwood for 3 days. For 3 days in a row, the sheep of group III were given 250 g of licorice. The helminth-infected sheep of the IV group were given 150 g of harmala with compound feed for 3 days. We fed animals of group V with 250 g of camel thorn for 5 days, and animals of group VI with 200 g of ephedra for 3 days. We also mixed ephedra with feed. Sheep infected with group VII helminths were kept under normal conditions and were not fed with anthelmintic plants. After 3 days of feeding with anthelmintic plants, the experimental animals and control groups were slaughtered and helminthological autopsy was performed. We collected Haemonchus, Strongylates and Trichucephaluses localized in the abomasum, small and large intestines of sheep and fixed them in Barbagol's solution in groups. In animals treated with garlic juice, anthelmintic efficacy against haemonchus was 84.9%, against strongylates 86.3%, against trichocephalus 52.7%. Compared with the control group, the effectiveness of wormwood against haemonchus reached 81.5%, and the severity of anthelmintic efficacy against strongylates and trichocephalus - 81.8 and 48.7%, respectively. Intensive effectiveness of licorice against haemonchus was 79.3%, anthelmintic efficacy against strongylates 77.1%, against trichocephalus 40.1%. The anthelmintic efficacy of harmala in the phase of fruit ripening reached 85.7% against haemonhus, against strongylates 84.3%, against trichocephalus 47.6%. Camel thorn, included in the animal feed base, gave 74.5% efficiency in hemonchosis, 72.4% in strongylatoses, and 40.1% in trichuriasis. The effectiveness of the intensity of ephedra against haemonchus was 80.6%, against strongylates 81.7%, against trichocephalus 50.3%.
Afficher plus [+] Moins [-]On the Efficacy of Turbulence Modelling for Sloshing Texte intégral
2022
Omar Ahmed Mahfoze | Wendi Liu | Stephen M. Longshaw | Alex Skillen | David R. Emerson
As part of a wider project to understand the applicability of utilising slosh-based damping for wing-like structures, simulations of partially filled tanks subjected to harmonically oscillating and vertical motion are presented. The Volume of Fluid modelling approach is used to capture the air–water interface and different turbulence models based on the Reynolds Averaged Navier–Stokes equations employed. No-model simulations are also conducted to demonstrate the efficacy of using turbulence models in the simulation of sloshing flows. Accuracy of the models is assessed by comparing with recent well-validated experimental data in terms of the damping effect of the sloshing. A wide range of excitation amplitudes are considered in the study to demonstrate the effectiveness of different turbulence models in representing the flow feature of weak and very violent sloshing. The results show that standard turbulence models can produce an excessive dissipation, especially at the interface, leading to inaccuracies in the estimation of sloshing dynamics of the violent sloshing. This issue is absent in the no-model simulations, and better results are obtained for all tested sloshing conditions, suggesting approaches to mitigate this interfacial dissipation within RANS-based modelling is an important consideration for future direction.
Afficher plus [+] Moins [-]Influence of teachers’ self-efficacy on secondary school students’ self-efficacy in biology in Ogbomoso, Nigeria Texte intégral
2022
Mulkah Adebisi Ahmed | Ahmed Abiodun Lawal | Rihanat Aduke Ahmed
It is widely proven by several studies that efficacy is an important factor in the teaching-learning process. Therefore, the goal of this study was to examine whether teachers’ self-efficacy contributes to the development of students’ self-efficacy in Biology. This study was a descriptive research with survey type which used proportionate and stratified sampling techniques to select 98 secondary schools in Ogbomoso, Nigeria. Proportionate, purposive, and simple random sampling techniques were used to select 207 biology teachers and 392 SSS I and II biology students based on gender. The data collected were analysed using mean scores, chi-square, and regression analysis at 0.05 level of significance. The findings revealed that: 1) there was a positive correlation between teachers’ self-efficacy and students’ self-efficacy in biology; 2) the level of teachers’ self-efficacy was moderately high; and 3) female students have higher self-efficacy than male students in biology. The study concluded that teachers’ self-efficacy influences their students’ self-efficacy. Thus, it is recommended that biology teachers should be responsible and pay more attention to the development of their students’ self-efficacy irrespective of students’ gender.
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