Propagation in cell culture and inactivation of foot and mouth disease virus and efficacy of foot and mouth disease vaccine [formalin and acetylethylenimine inactivators; calf kidney cell culture]
1984
Paprocka, G. (Instytut Weterynarii, Zdunska Wola (Poland))
The highest titre of A, O and C strains of foot and mouth disease virus propagated in a calf kidney cell culture was obtained after 18 h incubation at 37 degrees C. The virus inactivated with a 0.05% acetylethylenimine showed higher immunogenic properties after 12 month storage at 4 degrees C than virus inactivated with a 0.05% formalin
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