Studies on the physiological properties of the histamine receptor of ileal smooth muscle in dog
1984
Kim, J.H. (Kyongsang National Univ., Chinju (Korea R.). Dept. of Veterinary Medicine) | Park, Y.B. (Seoul National Univ., Seoul (Korea R.). Coll. of Medicine) | Kwun, J.K. (Seoul National Univ., Suwon (Korea R.). Coll. of Veterinary Medicine)
To validate the physiological properties of the histamine receptors of ileal smooth muscle in dog, the effect of adrenergic, cholineric and H-receptor antagonists on the responses of ileal smooth muscle strips to histamine were investigated. Histamine caused the contraction of ileal smooth muscle and the contractile responses increased between the concentration of histamine (10-7M and 10-5 M) with dosedependent manner in dog. The shorter the treatment interval of histamine, the lower the contractile activity until the treatment interval extended to 40 minutes
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