Histopathologic studies on the brain and lymphoid organ [of swine]
1982
Kwak, S.D. (Kyungbuk Animal Health Experimental Inst., Daegu (Korea R.)) | Lee, C.S. (Kyungbuk National Univ., Daegu (Korea R.). Coll. of Agriculture, Dept. of Veterinary Medicine)
This study was done to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the necrotic lesion and inclusion body in the lymphoid organs were carried out in the natural cases of hog cholera and experimental cases inoculated with ALD (challenge) virus and isolated virus strains. Electron microscopic findings of the intranuclear inclusion bodies in the retincular cell of spleen and lymph node were also observed in the experimental cases. The histological findings of necrosis of lymphoid organs were found to contain 35.0% in the natural and 37.5% in the experimental cases. Intranuclear inclusion bodies were found mainly in the reticular cells of lymhoid organ, the epithelium of bronchiole and alevolus, and the vascular endothelium of brain. These inclusion bodies were seen in 40.0% of the natural cases and in all of the experiment cases. The inclusion body appeared to be composed of activated nucleoli and chromatin granuls (interchromatin and perichromatin) by electron microscopy
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