Studies on reappearance of thymus after orchidectomy in ageing rats

Lee, M.H.; Kim, S.K. . Coll. of Agriculture; Jo, W.Y.

Studies on reappearance of thymus after orchidectomy in ageing rats

1989

Lee, M.H. | Kim, S.K. (Chungnam National Univ., Taejon (Korea R.). Coll. of Agriculture) | Jo, W.Y. (Chungbuk Animal Health Laboratory Chongju (Korea R.))

These studies were carried out to investigate the changes of blood pictures, histological findings and testosterone concentrations after orchidectomy in ageing rat. The total W.B.C. counts were 9.27 +- 12 x 10** (3)/mm** (3) in the control group, 9.54 +- 34 x 10** (3)/mm** (3) in the sham-operation group and 12.08 +- 28 x 10** (3)/mm** (3) in the orchidectomy group when it was checked 50days after the operation. The number of lymphocytes after orchidectomy began to increase gradually as time passes, thereafter markedly increased 10.12 +- 03 x 10** (3)/mm** (3) at 50 days after orchidectomy. The concentration of testosterone in serum began to decrease gradually after orchidectomy showed lowest level 1.68 +- 0.61 pg/ml at 50 days after orchidectomy while it was 5.82 +- 0.39 pg/ml in control group. The histological findings of thymus after orchidectomy marked increase of thymic lymphocyte, disapearance of fat cells and appearance of mitotic figures

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