Pharmacokinetic studies of enrofloxacin in healthy dogs and pyelonephritis dogs
1988
Baydan, E. | Kurtdede, A. | Kaya, S. | Borku, K. | Yarsan, E. | Pekkaya, S. (Ankara Univ., Faculty of Veterinary Medicine, Ankara (Turkey))
The aim of this study was to determine the pharmacokinetics of enrofloxacin after a single intravenous (IV) and intramascular (IM) injection at a dose level of 5 mg/kg body weight (bw) in healty dogs and dogs with pyelonephritis and to find out if there will be pharmacokinetic differences between healthy dogs and dogs with pyelonephritis. In the experiment, 8-10 month-old mongrel from both sexes and weighthing 16-28.5 kg body weight, were divided into control and studying groups. Enrofloxacin was given to control group by IV injection and to studying group by IM one. Following the administration of drag, blood samples of all dogs in this trial were collected into tubes at hours from 0,08 to 36
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