Blood serum protein status of broilers exposed to prolonged treatment with a low dose of ochratoxin A

Nedeljkovic-Trailovic, J.; Stevanovic, J.; Sinovec, Z.

Blood serum protein status of broilers exposed to prolonged treatment with a low dose of ochratoxin A

2000

Nedeljkovic-Trailovic, J. | Stevanovic, J. | Sinovec, Z. (Faculty of Veterinary Medicine, Belgrade (Yugoslavia))

The 42 day long trial was performed on hybro broilers divided into four groups. After a 14 day preexperimental period, the groups were offered feed contaminated by 0.5 ppm ochratoxin A (OA) for 0, 7, 14 or 21 days. Blood samples were taken after the period of toxin addition and the remaining birds from the control and experimental groups were normally fed mash without added OA until the 42nd day of the trial, when blood samples were taken again. The total level of serum proteins was not changed during of prolonged treatment with OA, but a significant increase of albumin together with a decrease of the gama-globulin fraction were noted. A/G ratio suggested that globulins were the dominant protein fraction in blood serum samples obtained from all broilers included in this trial. The concentrations of alfa and beta globulins in serum were within the physiological limits. It could be concluded that the low dietary OA level (0.5 ppm) had a possible cumulative, but not acute effect on blood serum protein status in broilers, dependent on the duration of exposure.

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