Effects of exposure to alternating-current, high-voltage, electric potential on experimental hypertension in Dahl-S rats
2001
Miura, N. (Kagoshima Univ. (Japan). Faculty of Agriculture) | Suzuki, S. | Hamada, Y. | Umemoto, C. | Kamimura, R. | Fujiki, M. | Misumi, K. | Sakamoto, H.
Antihypertensive effect of exposure alternating current, high-voltage, electrical potential (AC-HVEP) were investigated in Dahl salt-sensitive (Dahl-S) rats used as models of salt-induced hypertension. The animals were divided into two groups: rats exposure to AC-HVEP (AC-HVEP group) and a control group not exposed to AC-HVEP. Throughout the experimental period, water with an addition of 1.0% NaCl was given the animals. Progressive hypertension in the AC-HVEP group was significantly less serious than in the control group. In addition, histopathological examination showed greater restriction of lesions in the AC-HVEP than in the control group. Our results suggest that AC-HVEP exposure can suppress progressive hypertension secondary to chronic renal failure.
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