Studies on the postnatal development of the Leydig cell in rabbits
2005
Tae, H.J. (Chonbuk National University, Jeonju, Republic of Korea) | Ahn, D.C. (Kangwon National University, Chuncheon, Republic of Korea) | Park, Y.J. (Chonbuk National University, Jeonju, Republic of Korea) | Kang, H.S. (Chonbuk National University, Jeonju, Republic of Korea) | Kim, N.S. (Chonbuk National University, Jeonju, Republic of Korea) | Park, S.Y. (Chonbuk National University, Jeonju, Republic of Korea) | Yang, H.H. (Chonbuk National University, Jeonju, Republic of Korea) | Kim, I.S. (Chonbuk National University, Jeonju, Republic of Korea), E-mail: iskim@chonbuk.ac.kr
Changes in the rabbit Leydig cell from birth to adulthood were studied in New Zealand white rabbits of 1, 7, 21, 35, 49, 70, 105, 147, 196, and 252 days (n = 8 rabbits per group) of age. The objectives of this study were to understand the fate of the fetal Leydig cells, to determine the changes in serum testosterone levels, and leutenizing hormone-stimulated testosterone production per testis in vitro, and to quantify adult Leydig cells by number and average volume with age. Testes of rabbits were fixed by whole body perfusion using a fixative containing 2.5% glutaraldehyde in cacodylate buffer, processed and embedded in Epon-araldite.
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