Effect of temperature on the amount of 146S particles in swine trivalent foot and mouth disease oil emulsion vaccine
2001
Chaiya Sangaprakhon(Department of Livestock Development, Bangkok (Thailand). Foot and Mouth Disease Center, Nakhonratchasima. Vaccine Quality Control Section) | Kritsada Limpananont(Department of Livestock Development, Bangkok (Thailand). Foot and Mouth Disease Center, Nakhonratchasima. Vaccine Quality Control Section)
Temperature effected the amount of 146S particles in Swine Trivalent Foot and Mouth Disease Oil Emulsion Vaccine. It was found that after storage the vaccine at 4 deg C, 15 deg C and 20 deg C for 35 days, the amount of 146S particles measured by sucrose density gradient ultracentrifugation method decreased a little when compared to those at pre-storage. After storing the vaccine at 25 deg C for 5, 14, 28 and 35 days, the average amount of 146S particles were 11.93, 41.76, 58.24 and 64.77 percent decrease, respectively, Whereas they were 44.41, 63.97, 68.16 and 100 percent decrease after storing the vaccine at 37 deg C for 1, 5, 10 and 14 days, respectively.
Показать больше [+] Меньше [-]