Molecular differentiation of Korean Newcastle disease virus (NDV) by restriction enzyme analysis and pathotype-specific RT-PCR
2006
Kwon, H.J. (Seoul National University, Seoul, Republic of Korea) | Cho, S.H. (Seoul National University, Seoul, Republic of Korea) | Kim, S.J. (Seoul National University, Seoul, Republic of Korea), E-mail: kimsja@snu.ac.kr
Newcastle disease virus (NDV) is a single-stranded negative sense RNA virus, which has been classified as a member of the Avulavirus genus of the Paramyxoviridae family. It is also one of the most important pathogens in the poultry industry. The glycoproteins, fusion (F) and hemagglutinin-neuraminidase (HN), determine the virulence of NDV, and the relevant molecular structures have already been determined. NDV isolates differ in terms of virulence, and at least 2 of 9 genotypes (Ⅰ-Ⅸ) have been shown to cocirculate.
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