Anti-allergic Activity of Oriental Medicinal Herbs
2006
Kim, Y.M. (Duksung Women's University, Seoul, Republic of Korea), E-mail: [email protected]
The effects of extracts from various Oriental medicinal herbs on mast-cell-mediated allergic reactions were investigated in this study. Out of these extracts, the medicinal herb Atractylodis rhizoma alba exhibited the most potent activity in the cells, with IC∧50 values of 20.5 ㎍/㎖ by DNP-BSA and 33.04 ㎍/㎖ by compound 48/80. Similar to the in vitro activity, Atractylodis rhizoma alba inhibited compound-48/80-induced systemic anaphylaxis by 31.3% at 300 mg/kg in mice.
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